Classification,biosynthesis,and biological functions of triterpene esters in plants  

作　　者：Jia Liu Xue Yin Chengxi Kou Ramesha Thimmappa Xin Hua Zheyong Xue 

机构地区：[1]Key Laboratory of Saline-alkali Vegetation Ecology Restoration(Northeast Forestry University),Ministry of Education,Harbin 150040,China [2]Heilongjiang Key Laboratory of Plant Bioactive Substance Biosynthesis and Utilization,Northeast Forestry University,Harbin 150040,China [3]Amity Institute of Genome Engineering,Amity University,Noida,UP India 201313,India [4]State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs,Beijing 100700,P.R.China

出　　处：《Plant Communications》2024年第4期67-93,共27页植物通讯（英文）

基　　金：supported by the National Key Research and Development Program of China (2023YFA0915800);the National Natural Science Foundation of China (32241040 and 31970314);Key project at central government level:The ability establishment of sustainable use for valuable Chinese medicine resources (2060302)。

摘　　要：Triterpene esters comprise a class of secondary metabolites that are synthesized by decorating triterpene skeletons with a series of oxidation,glycosylation,and acylation modifications.Many triterpene esters with important bioactivities have been isolated and identified,including those with applications in the pesticide,pharmaceutical,and cosmetic industries.They also play essential roles in plant defense against pests,dis-eases,physical damage(as part of the cuticle),and regulation of root microorganisms.However,there has been no recent summary of the biosynthetic pathways and biological functions of plant triterpene esters.Here,we classify triterpene esters intofive categories based on their skeletons andfind that C-3 oxidation may have a significant effect on triterpenoid acylation.Fatty acid and aromatic moieties are common li-gands present in triterpene esters.We further analyze triterpene ester synthesis-related acyltransferases(TEsACTs)in the triterpene biosynthetic pathway.Using an evolutionary classification of BAHD acyltrans-ferases(BAHD-ATs)and serine carboxypeptidase-like acyltransferases(SCPL-ATs)in Arabidopsis thaliana and Oryza sativa,we classify 18 TEsACTs with identified functions from 11 species.All the triterpene-skel-eton-related TEsACTs belong to BAHD-AT clades IIIa and I,and the only identified TEsACT from the SCPL-AT family belongs to the CP-I subfamily.This comprehensive review of the biosynthetic pathways and bioactivities of triterpene esters provides a foundation for further study of their bioactivities and applica-tions in industry,agricultural production,and human health.

关 键 词：triterpene esters ACYLTRANSFERASES CLASSIFICATION BIOSYNTHESIS biological functions 

分 类 号：Q94[生物学—植物学]