Basin-scale exposure risk of psychiatric pharmaceuticals and illicit drugs in tap water in Eastern China  

作　　者：Wei Wang Zeyuan Wang Feng Chen Fangxing Yang 

机构地区：[1]Zhejiang Institute of Hydraulics&Estuary(Zhejiang Institute of Marine Planning and Design),Hangzhou,310008,China [2]Key Laboratory of Marine Ecosystem Dynamics,Second Institute of Oceanography,Ministry of Natural Resources,Hangzhou,310012,China [3]Key Laboratory of Environment Remediation and Ecological Health,Ministry of Education,College of Natural Resources and Environmental Science,Zhejiang University,310058,Hangzhou,China [4]Hangzhou Ecological and Environmental Monitoring Center of Zhejiang Province,310058,Hangzhou,China [5]Innovation Center of Yangtze River Delta,Zhejiang University,314100,Jiashan,China

出　　处：《Emerging Contaminants》2024年第3期40-45,共6页新兴污染物（英文）

基　　金：supported by grants from the National Natural Science Foundation of China(41977341);Public Technology Research Project of Zhejiang Province(LGC19B070004),Key Laboratory of Marine Ecosystem Dynamics(MED202305);State Key Laboratory of Environmental Chemistry and Ecotoxicology,Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences(KF2018-15).

摘　　要：A total of twenty-three psychiatric pharmaceuticals and illicit drugs were analyzed in tap water covering seven basins in Eastern China.The residual concentrations of these substances were detected up to 22.4 ng L^(-1).Among the substances,benzodiazepines were more often detected with higher median concentrations than those of illicit drugs.Generally,the higher residual levels of psychoactive substances were detected in the upstream of the basins compared with the downstream.For example,the concentrations of diazepam,temazepam,and oxazepam in the downstream were much higher than those in the upstream in OJ.Among the basins,YH was the most polluted region.Exposure assessment indicated the median exposure doses of diazepam and temazepam were from 85 to 99 and 3.5e4.1 pg kg^(-1) bw d^(-1) in the basins,respectively.Benchmark quotient for the nine detected substances was calculated in each basin with the range from 0.0001 to 0.0389,indicating low risk in the tap water for human health under current concentrations.

关 键 词：Psychiatric pharmaceuticals Illicit drugs Psychoactive substances Tap water Risk assessment 

分 类 号：X799.5[环境科学与工程—环境工程]