四环素类抗菌药物儿科临床应用专家共识(2024年版)  

Expert consensus on clinical application of tetracycline antibiotics in children(2024 Edition)

作　　者：中国药学会儿童药物专业委员会 中华医学会儿科学分会呼吸学组合理用药协作组 中国妇幼保健协会儿童变态反应专业委员会呼吸学组 《中国实用儿科杂志》编辑委员会 张海邻[2] 陈瑞杰[2] 董晓艳 邹映雪[4] 付红敏 陆小霞 田曼[7] 陈莉娜[8] 陆权 李智平[9] 符州 Pediatric Pharmaceutical Committee of Chinese Pharmaceutical Association;Cooperative Group of Rational Drug Use,Respiratory Group,Pediatrics Society of Chinese Medical Association;Respiratory Group of Professional Committee of Child Allergology,China Meternal and Child Health Association;LU Quan;LI Zhi-ping;FU Zhou

机构地区：[1]不详 [2]温州医科大学附属第二医院育英儿童医院 [3]上海交通大学医学院附属儿童医院 [4]天津市儿童医院天津大学儿童医院 [5]昆明医科大学附属儿童医院 [6]华中科技大学同济医学院附属武汉儿童医院 [7]南京医科大学附属儿童医院 [8]四川大学华西第二医院 [9]复旦大学附属儿科医院 [10]重庆医科大学附属儿童医院

出　　处：《中国实用儿科杂志》2024年第9期641-651,共11页Chinese Journal of Practical Pediatrics

摘　　要：四环素类抗菌药物对包括肺炎支原体、衣原体在内的多种病原体有较强的抗菌作用,在儿科临床的应用逐渐增多。由于儿童不同于成人的生理特点,亟需一个专门针对儿童四环素类抗菌药物临床应用的指导文件。该共识从四环素类药物的药学特性、作用机制、抗菌活性、耐药现状和耐药机制在儿童感染性疾病中的作用、不良反应及超说明书用药等方面,对该类药物在儿科临床的应用给出了全面建议,以指导临床合理使用。Tetracycline antibiotics have strong antibacterial effect on a variety of pathogens including mycoplasma pneumoniae and chlamydia,and their application in children is gradually increasing.Due to the different physiological characteristics of children from adults,there is an urgent need for a special guidance document for the clinical use of tetracycline antibiotics in children.The consensus gives comprehensive recommendations on the clinical application of tetracycline drugs in pediatrics from the aspects of pharmaceutical characteristics,mechanism of action,antibacterial activity,status and mechanism of drug resist ance,effects in children with infectious diseases,adverse reactions and off-label drug use,so as to guide clinical rational use.

关 键 词：抗菌药物 四环素类 共识 儿童 

分 类 号：R72[医药卫生—儿科]