正清风痛宁定点介入联合高压氧治疗膝骨性关节炎疗效观察  

Observation on the Clinical Efficacy of Targeted Intervention with Zhengqing Fengtongning Injection Combined with Hyperbaric Oxygen Therapy for Knee Osteoarthritis

作　　者：李洁 滕进忠 方玉平 周乐花 LI Jie;TENG Jinzhong;FANG Yuping;ZHOU Lehua(Nanchang 334 Hospital,Nanchang 330024,China)

机构地区：[1]南昌三三四医院,南昌330024

出　　处：《江西中医药大学学报》2024年第5期54-57,共4页Journal of Jiangxi University of Chinese Medicine

基　　金：江西省中医药管理局科技计划项目(2023B1081)。

摘　　要：目的:观察正清风痛宁注射液定点介入联合高压氧治疗膝骨性关节炎(KOA)的临床疗效。方法:择取南昌三三四医院2022年1月—2023年1月收治的KOA患者90例,采用随机数字法分为A组、B组和C组,各30例。3组患者均接受常规治疗,A组加用正清风痛宁注射液定点介入治疗,B组给予高压氧治疗,C组给予正清风痛宁注射液定点介入联合高压氧治疗,比较3组临床疗效、膝关节功能[骨关节炎指数、视觉模拟评分法(VAS)评分]及生活质量(关节炎影响评估表评分)。结果:治疗2个疗程后,3组总有效率比较,C组为93.33%,A组、B组分别为76.67%和66.67%,C组优于A组、B组,差异均有统计学意义(P<0.05);3组骨关节炎指数、VAS评分均低于治疗前(P<0.05),且C组低于A组、B组,差异均有统计学意义(P<0.05);3组生活质量评分均低于治疗前(P<0.05),且C组低于A组、B组,差异均有统计学意义(P<0.05)。结论:正清风痛宁注射液定点介入联合高压氧治疗KOA效果显著,可改善膝关节功能,提高患者生活质量。Objective:To observe the clinical efficacy of Zhengqing Fengtongning Injection combined with hyperbaric oxygen therapy in the treatment of knee osteoarthritis(KOA).Methods:Ninety patients with knee osteoarthritis admitted to Nanchang 334 Hospital from January 2022 to January 2023 were randomly divided into Group A,Group B,and Group C,with 30 patients in each group.All three groups of patients received routine treatment,with group A receiving targeted intervention with Zhengqing Fengtongning Injection,group B receiving hyperbaric oxygen therapy,and group C receiving targeted intervention with Zhengqing Fengtongning Injection combined with hyperbaric oxygen therapy.The clinical efficacy,knee joint function[osteoarthritis index,visual analog scale(VAS)],and quality of life(arthritis impact assessment form)were compared among the three groups.Results:After two treatment courses,the total effective rate of the three groups was compared.Group C was 93.33%,while group A and group B were 76.67%and 66.67%,respectively.Group C was superior to group A and group B,and the difference was statistically significant(P<0.05);The osteoarthritis index and VAS of the three groups were lower than before treatment(P<0.05),and group C was lower than group A and group B,with statistically significant differences(P<0.05);The quality of life scores of all three groups were lower than before treatment(P<0.05),and group C was lower than group A and group B,with statistically significant differences(P<0.05).Conclusion:The targeted intervention of Zhengqing Fengtongning Injection combined with hyperbaric oxygen therapy has significant effects on the treatment of knee osteoarthritis,improving knee joint function and enhancing patients'quality of life.

关 键 词：正清风痛宁注射液 高压氧治疗 膝骨性关节炎 膝关节功能 生活质量 

分 类 号：R274.9[医药卫生—中西医结合]