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作 者:王天召 戴婷婷 WANG Tian-zhao;DAI Ting-ting(Urology and Andrology Department,Ningxia TCM Hospital and Research Institute of Traditional Chinese Medicine,Yinchuan 750021,Ningxia Hui Autonomous Region,China;Department of Traditional Chinese Medicine,Community Health Service Center,Zhongshan South Street,Xingqing District,Yinchuan First People's Hospital,Yinchuan 750003,Ningxia Hui Autonomous Region,China)
机构地区:[1]宁夏中医医院暨中医研究院泌尿男科,宁夏银川750021 [2]银川市第一人民医院兴庆区中山南街社区卫生服务中心中医科,宁夏银川750003
出 处:《罕少疾病杂志》2024年第10期103-105,共3页Journal of Rare and Uncommon Diseases
摘 要:目的探讨坦索罗辛联合骶神经根磁刺激对Ⅲ型前列腺炎伴性功能的治疗效果。方法选取2021年1月~2023年1月本院收治的100例Ⅲ型CP患者作为研究对象。据患者初次诊断的顺序编号,按奇偶数法分为观察组与对照组,各50例。其中对照组使用坦索罗辛治疗,观察组使用坦索罗辛联合骶神经根磁刺激治疗。观察两组治疗前后疗效、慢性前列腺炎症状指数(NIH-CPSI)和国际勃起功能指数-5(IIEF-5)评分及血清白介素2、8(IL-2、IL-8)和肿瘤坏死因子(TNF-α)水平。结果观察组总有效率明显高于对照组(P<0.05)。治疗后,两组NIH-CPSI评分较治疗前显著降低,IIEF-5评分则较治疗前显著升高(P<0.05);且观察组NIH-CPSI评分显著低于对照组,IIEF-5评分则明显高于对照组(P<0.05)。治疗后,两组前各项炎症因子均显著降低(P<0.05),且观察组前各项炎症因子显著低于对照组(P<0.05)。结论坦索罗辛联合骶神经根磁刺激可有效改善前列腺炎症状和勃起功能,还能降低血清炎症因子水平。Objective To investigate the therapeutic effect of tamsulosin combined with sacral nerve radiculum magnetic stimulation on sexual function of type Ⅲ prostatitis.Methods A total of 100 patients with type Ⅲ CP admitted to our hospital from January 2021~January 2023 were selected as the research subjects.According to the sequential number of the patient's initial diagnosis,it was divided into observation group and control group according to odd and even numbers,with 50 cases each.The control group was treated with tamsulosin,and the observation group was treated with tamsulosin combined with sacral nerve root magnetic stimulation.The efficacy of the two groups before and after treatment,chronic prostatitis symptom index(NIH-CPSI)and international erectile function index-5(IIEF-5)scores,serum interleukin 2,8(IL-2,IL-8)and tumor necrosis factor(TNF-α)levels were observed before and after treatment.Results The total effective rate of the observation group was significantly higher than that of the control group(P<0.05).After treatment,the NIH-CPSI score of the two groups was significantly lower than that before treatment,and the IIEF-5 score was significantly higher than that before treatment(P<0.05).The NIH-CPSI score in the observation group was significantly lower than that in the control group,and the IIEF-5 score was significantly higher than that in the control group(P<0.05).After treatment,the first inflammatory factors in both groups were significantly reduced(P<0.05),and the inflammatory factors in the observation group were significantly lower than those in the control group(P<0.05).Conclusion Tamsulosin combined with sacral nerve root magnetic stimulation can effectively improve prostatitis symptoms and erectile function,and also reduce serum inflammatory factor levels.
关 键 词:坦索罗辛 骶神经根磁刺激 Ⅲ型前列腺炎伴性功能障碍
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