白癜风发病机制的研究进展  

Research Progress of Pathogenesis of Vitiligo

作　　者：木亚赛尔·艾合买提 热孜万古丽·乌买尔[2] Muyasaier AIHEMAITI;Reziwanguli WUMAIER(Xinjiang Medical University,Urumqi 830011,China;Department of Dermatology,Xinjiang Uygur Autonomous Region Uyghur Medical Hospital,Urumqi 830049,China)

机构地区：[1]新疆医科大学,乌鲁木齐830011 [2]新疆维吾尔自治区维吾尔医医院皮肤科,乌鲁木齐830049

出　　处：《医学综述》2024年第21期2620-2623,2630,共5页Medical Recapitulate

摘　　要：白癜风是临床上常见的一种皮肤病,病程长、治疗难度大,严重影响患者的心理健康。目前白癜风确切的发病机制尚未完全明确,但已揭示的发病机制涉及多种学说,包括遗传学、自身免疫反应、神经精神因素、氧化应激反应及黑色素细胞死亡等方面。白癜风的治疗是一个复杂而长期的过程,需要医学、心理和社会多方面的支持与合作。因此,深入研究其发病机制,寻找新的生物标志物,有助于改善患者生活质量,并为白癜风的诊断和治疗提供新思路。Vitiligo is a common skin disease in the clinic.The course of the disease lasts for a long time,and it is difficult to treat,which seriously affects the mental health of the patients.At present,the exact pathogenesis of vitiligo is not fully understood,but the revealed pathogenesis involves a variety of theories,including genetics,autoimmune response,neuropsychiatric factors,oxidative stress response and melanocyte death etc.The treatment of vitiligo is a complex and long-term process that requires many support and cooperation from medical,psychological and social aspects.Therefore,in-depth research on the pathogenesis and finding new biomarkers will help to improve the patients′quality of life,and provide new ideas for the diagnosis and treatment of vitiligo.

关 键 词：白癜风 氧化应激 遗传因素 免疫因素 黑色素细胞 维生素D 

分 类 号：R751[医药卫生—皮肤病学与性病学]