钬激光结合FFU和DFU治疗肾结石的效果对比  

Comparison the Effects of Holmium Laser Combined with FFU and DFU in the Treatment of Kidney Stones

作　　者：李永 LI Yong(Xuzhou Mining Hospital,Xuzhou 221000,China)

机构地区：[1]徐州市矿山医院,江苏徐州221000

出　　处：《中外医学研究》2024年第28期122-125,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨钬激光结合纤维输尿管软镜(FFU)和电子输尿管软镜(DFU)治疗肾结石的效果对比。方法:选取2022年6月—2023年6月徐州市矿山医院收治的110例肾结石患者,按信封随机法分成试验组(55例)、对照组(55例)。对照组施行钬激光结合FFU术,试验组施行钬激光结合DFU术。对比两组临床指标、寻石成功率、结石清除率、应激指标和安全性等。结果:两组术中出血量、住院花费和住院用时对比,差异无统计学意义(P>0.05),试验组手术操作用时短于对照组,差异有统计学意义(P<0.05)。两组寻石成功率对比,差异无统计学意义(P>0.05),试验组结石清除率为96.36%,高于对照组的85.45%,差异有统计学意义(P<0.05)。术后1 d,两组各项应激指标均升高,但试验组血清去甲肾上腺素(NE)、促肾上腺皮质激素(ACTH)和皮质醇(Cor)指标低于对照组,差异有统计学意义(P<0.05)。试验组石街形成、输尿管损伤和血尿等并发症总发生率为3.64%,低于对照组的14.55%,差异有统计学意义(P<0.05)。结论:在肾结石疾病的治疗中,钬激光结合FFU和DFU均可取得一定的疗效,但钬激光结合DFU术的结石清除率更高,操作用时更短,应激反应更少,安全性更好。Objective:To comparison the effects of holmium laser combined with fiber ureteroscope(FFU)and disposable flexible ureteroscope(DFU)in the treatment of kidney stones.Method:A total of 110 cases of kidney stones admitted to Xuzhou Mining Hospital from June 2022 to June 2023 were selected,and divided into an experimental group(55 cases)and a control group(55 cases)by random envelope method.The control group underwent holmium laser combined with FFU surgery,while the experimental group underwent holmium laser combined with DFU surgery.The clinical indicators,stone search success rate,stone related clearance rate,stress indicators,and safety were compared between the two groups.Result:There were no differences in the amount of intraoperative bleeding,hospitalization expenses,and hospitalization time between the two groups(P>0.05).The experimental group had shorter surgical operation time than the control group,and the difference was statistically significant(P<0.05).There was no difference in the success rate of stone exploration between the two groups(P>0.05).The stone clearance rate in the experimental group was 96.36%,which was higher than 85.45%in the control group,the difference was statistically significant(P<0.05).At 1 d after surgery,the stress indexes of both groups were increased,but the serum norepinephrine(NE),adrenocorticotrophin(ACTH)and cortisol(Cor)indexes of experimental group were lower than those of control group,the differences were statistically significant(P<0.05).The total incidence of complications such as stone street formation,ureteral injury and hematuria in experimental group was 3.64%,which was lower than 14.55%in control group,and the difference was statistically significant(P<0.05).Conclusion:In the treatment of kidney stones,both holmium laser combined with FFU and DFU can achieve certain therapeutic effects.However,holmium laser combined with DFU has a higher stone clearance rate,shorter operation time,fewer stress reactions,and better safety.

关 键 词：肾结石 钬激光 电子输尿管软镜 安全性 纤维输尿管软镜 

分 类 号：R699.2[医药卫生—泌尿科学]