A型肉毒毒素注射治疗痉挛性斜颈的引导技术研究进展  

Research progress on guidance technology for botulinum toxin A injection in the treatment of cervical dystonia

作　　者：沈婷婷 吴乾昌 刘晶[1] 米宝明 阎俊[3] 罗蔚锋[1] SHEN Tingting;WU Qianchang;LIU Jing;MI Baoming;YAN Jun;LUO Weifeng(Department of Neurology,The Second Affiliated Hospital of Soochow University,Suzhou 215004,China)

机构地区：[1]苏州大学附属第二医院神经内科,苏州215004 [2]苏州大学附属第二医院核医学科,苏州215004 [3]南京医科大学附属脑科医院老年医学科

出　　处：《临床神经外科杂志》2024年第5期588-592,共5页Journal of Clinical Neurosurgery

基　　金：江苏省重大精神神经技术重点实验室项目(2060503)。

摘　　要：痉挛性斜颈(CD)是临床常见的一种局灶性肌张力障碍疾病,主要由于颈部肌肉不自主收缩引起的异常姿势或运动,大多数为特发性。CD的治疗方法有口服药物、A型肉毒毒素(BoNT-A)注射、手术等方法。BoNT-A注射起效快、持续时间长、副作用小、重复性好,是目前首选的治疗方法。然而不同研究中BoNT-A注射的疗效差异较大,为提高BoNT-A注射疗效,临床上各类引导技术应运而生,本文就各类BoNT-A注射引导技术的优势和不足进行综述。Cervical dystonia(CD)is a common focal dystonia in clinical practice,which is mainly caused by involuntary contraction of neck muscles,manifesting abnormal posture or movement.Most of them are idiopathic.The treatment of CD includes oral medication,botulinum toxin A(BoNT-A)injection,surgery and so on.BoNT-A injection has rapid onset,long duration,few side effects,and good repeatability,which is currently the preferred treatment.However,the efficacy of BoNT-A injection varies greatly among different studies.In order to improve the efficacy of BoNT-A injection,various clinical guidance techniques have been developed.This article reviews the advantages and disadvantages of various BoNT-A injection guidance techniques.

关 键 词：痉挛性斜颈 A型肉毒毒素 注射引导技术 

分 类 号：R651[医药卫生—外科学]