颅内原发性罗道病1例并文献复习  

Intracranial primary Rosai-Dorfman Disease:case report of one case and literature review

作　　者：李迪 冷昭富 姜彦文 秦虎[1] 王昀[1] 汪永新[1] LI Di;LENG Zhaofu;JIANG Yanwen;QIN Hu;WANG Yun;WANG Yongxin(Department of Neurosurgery,The First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)

机构地区：[1]新疆医科大学第一附属医院神经外科,乌鲁木齐830054

出　　处：《临床神经外科杂志》2024年第5期593-595,600,共4页Journal of Clinical Neurosurgery

基　　金：新疆维吾尔自治区区域协同创新专项项目(2021E01013)。

摘　　要：目的探讨颅内原发性罗道病(RDD)的临床表现、影像学、病理、免疫组化、治疗及预后。方法回顾性分析新疆医科大学第一附属医院收治的1例颅内原发性RDD患者的临床资料,并对相关文献进行复习。结果患者头部磁共振示,左侧颞顶部占位性病变,行手术完全切除病变。术后病理诊断为RDD,免疫组化示S-100(+)、CD68(+)。结论RDD属良性病变,其诊断主要依据病理及免疫组化。外科手术切除是目前治疗RDD最有效的治疗方式,对于多发或者无法切除的病变组织,可适当给予放疗及化疗辅助。Objective To investigate the clinical manifestations,imaging,clinicopathological,immunohistochemistry,treatment and prognosis of intracranial primary Rosai-Dorfman disease(RDD).Methods The clinical data of a patient with intracranial primary RDD admitted to The First Affiliated Hospital of Xinjiang Medical University were analyzed retrospectively,and the relevant literature were reviewed.Results The magnetic resonance imaging of the head showed an occupying lesion on the left parietal temporal area,and surgery was performed to completely remove the lesion.Postoperative pathology was diagnosed as RDD,immunohistochemistry showed S-100(+),CD68(+).Conclusions RDD is a benign disease,and its diagnosis is mainly based on pathology and immunohistochemistry.Surgical resection is currently the most effective treatment for RDD.For multiple or unresectable lesions,radiotherapy and chemotherapy can be given as an adjunct.

关 键 词：颅内占位 罗道病 治疗 预后 

分 类 号：R651[医药卫生—外科学]