建议在烧伤休克期不常规预防性全身使用抗菌药物  

No administering prophylactic systemic antibiotics routinely during the shock phase after burn injury

作　　者：罗高兴 李海胜 袁志强 彭毅志 Luo Gaoxing;Li Haisheng;Yuan Zhiqiang;Peng Yizhi(Institute of Burn Research,State Key Laboratory of Trauma and Chemical Poisoning,the First Affiliated Hospital of Army Medical University(the Third Military Medical University),Chongqing Key Laboratory for Wound Repair and Tissue Regeneration,Chongqing 400038,China)

机构地区：[1]陆军军医大学(第三军医大学)第一附属医院全军烧伤研究所,创伤与化学中毒全国重点实验室,重庆市创面修复与组织再生重点实验室,重庆400038

出　　处：《中华烧伤与创面修复杂志》2024年第10期911-914,共4页Chinese Journal of Burns And Wounds

基　　金：国家自然科学基金面上项目(82372515,82072171)。

摘　　要：感染是烧伤最常见的并发症,但烧伤后通常不会迅速引起全身性感染。国内传统上往往在烧伤休克期即常规预防性全身使用抗菌药物,以防治烧伤感染的发生发展,但临床证据及国际烧伤感染防治专家共识与指南均强烈反对烧伤后立即常规预防性全身使用抗菌药物。笔者单位停止在严重烧伤休克期常规预防性全身使用抗菌药物后,并未观察到感染及相关并发症发生率的明显增加。故笔者团队建议,除一些特殊患者外,在烧伤休克期不常规预防性全身使用抗菌药物。Infection is the most common complication following burn injury,while it is rare to induce immediately systemic infection after burn injury.Domestically,the burn patients especially the major burn patients are conventionally administered systemic antibiotics prophylactically during the shock phase after burn injury.However,the clinical evidences and all the international expert consensuses and guidelines on burn infections object strongly and clearly administration of systemic antibiotics prophylactically.The incidences of systemic infection and sepsis did not increase significantly after prohibiting prophylactical administration of systemic antibiotics routinely during the shock phase after burn injury based on the authors unit's clinical data of more than 100 major burn patients.Herein,we propose that the burn patients should not be routinely administered systemic antibiotics prophylactically during the burn shock phase.

关 键 词：烧伤 感染 脓毒症 预防性全身使用抗菌药物 

分 类 号：R644[医药卫生—外科学]