脓毒症分型:精准治疗之基石  

Classification of sepsis:the cornerstone for precise treatment

作　　者：姚咏明[1] 张卉 董宁[1] Yao Yongming;Zhang Hui;Dong Ning(Medical Innovation Research Division and the Fourth Medical Center of PLA General Hospital,Beijing 100853,China)

机构地区：[1]解放军总医院医学创新研究部、第四医学中心,北京100853

出　　处：《中华烧伤与创面修复杂志》2024年第10期915-919,共5页Chinese Journal of Burns And Wounds

基　　金：国家自然科学基金重点项目(82130062,82241062);国家重点研发计划(2022YFA1104604)。

摘　　要：脓毒症是异质性较大的临床综合征。对脓毒症患者进行分型,是提高脓毒症临床处置效率的前提,也是实现脓毒症精准治疗的基础。近年来,国内外许多研究根据脓毒症患者的临床特征、实验室指标、基因组学等数据对患者进行分型。该文简要分析了目前认可度较高的几种脓毒症分型方式,以期为构建脓毒症规范化诊断和治疗体系提供新思路。Sepsis appears to be a heterogeneous clinical syndrome.The classification of patients with sepsis is the prerequisite for improving the efficiency of clinical management and is also the basis for achieving precise treatment of sepsis.In recent years,many studies at home and abroad have classified patients with sepsis based on data including their clinical characteristics,laboratory biomarkers,and genomics.This article briefly analyzed several sepsis classification methods that are currently well recognized,with a view to providing new ideas for building a standardized diagnosis and treatment system for sepsis.

关 键 词：脓毒症 内表型 外表型 精准治疗 

分 类 号：R459.7[医药卫生—急诊医学]