游离皮瓣在糖尿病足溃疡患者保肢治疗中的应用研究进展  

Research advances on the application of free flaps in limb salvage treatment of patients with diabetic foot ulcers

作　　者：刘欣[1] 黄广涛 吴军 Liu Xin;Huang Guangtao;Wu Jun(Department of Burns and Plastic Surgery,Department of Wound Repair,the First Affiliated Hospital of Shenzhen University,Shenzhen 518035,China)

机构地区：[1]深圳市第二人民医院(深圳大学第一附属医院)烧伤整形创面修复科,深圳518035

出　　处：《中华烧伤与创面修复杂志》2024年第10期985-990,共6页Chinese Journal of Burns And Wounds

基　　金：河套创新合作区项目(HTHZQSWS-KCCYB-2023060);国家自然科学基金面上项目(82172214,82472545)。

摘　　要：糖尿病足溃疡(DFU)是糖尿病的严重并发症之一,治疗难度大、截肢风险高。目前指南建议,根据DFU中组织坏死程度及血管闭塞平面、患者年龄及全身脏器功能综合评估截肢平面。然而,截肢后的DFU患者生存率及生活质量均受到较大影响。通过查阅国内外文献并对DFU保肢治疗的经验进行总结,该团队认为采用游离皮瓣移植进行保肢治疗,对于部分严重DFU患者而言意义重大。此外,该文还重点分析了DFU患者接受游离皮瓣移植手术的适应证和围手术期注意事项。Diabetic foot ulcers(DFUs)is one of the severe complications of diabetes,which is difficult to treat and associated with a high risk of amputation.Current guidelines recommend that the plane of amputation be comprehensively assessed based on the degree of tissue necrosis and plane of vascular occlusion in DFUs,the age and systemic organ function of patients.However,the survival and quality of life of DFU patients suffering from amputation will be significantly affected.After reviewing the national and international literature and summarizing the experience of limb-salvage treatment of DFUs,we believe that free flap transplantation is of great significance for limb-salvage treatment to some patients with severe DFUs.In addition,this article also focus on analyzing the indications and perioperative precautions for patients with DFUs undergoing free flap transplantation.

关 键 词：糖尿病足 溃疡 外科皮瓣 保肢治疗 创面修复 

分 类 号：R587.2[医药卫生—内分泌] R658.3[医药卫生—内科学]