PCMD:A multilevel comparison database of intraand cross-species metabolic profiling in 530 plant species  

作　　者：Yue Hu Yao Ruan Xin-Le Zhao Feng Jiang Dongxu Liu Qiang Zhu Qing-Ye Zhang Qing-Yong Yang 

机构地区：[1]National Key Laboratory of Crop Genetic Improvement,Hubei Hongshan Laboratory,Huazhong Agricultural University,Wuhan 430070,Hubei,China [2]Hubei Key Laboratory of Agricultural Bioinformatics and Hubei Engineering Technology Research Center of Agricultural Big Data,College of Informatics,Huazhong Agricultural University,Wuhan 430070,China [3]Yazhouwan National Laboratory,Sanya 572024,China

出　　处：《Plant Communications》2024年第10期33-44,共12页植物通讯（英文）

基　　金：supported by the National Natural Science Foundation of China(32322061 and 32070559);the Fundamental Research Funds for the Central University HZAU(2662022XXYJ007 and 2662023XX PY001);the China Postdoctoral Science Foundation(2024M751038)。

摘　　要：Comparative metabolomics plays a crucial role in investigating gene function,exploring metabolite evolution,and accelerating crop genetic improvement.However,a systematic platform for intra-and crossspecies comparison of metabolites is currently lacking.Here,we report the Plant Comparative Metabolome Database(PCMD;http://yanglab.hzau.edu.cn/PCMD),a multilevel comparison database based on predicted metabolic profiles of 530 plant species.The PCMD serves as a platform for comparing metabolite characteristics at various levels,including species,metabolites,pathways,and biological taxonomy.The database also provides a number of user-friendly online tools,such as species comparison,metabolite enrichment,and ID conversion,enabling users to perform comparisons and enrichment analyses of metabolites across different species.In addition,the PCMD establishes a unified system based on existing metabolite-related databases by standardizing metabolite numbering.The PCMD is the most speciesrich comparative plant metabolomics database currently available,and a case study demonstrates its ability to provide new insights into plant metabolic diversity.

关 键 词：comparative metabolomics plant database multilevel comparison metabolite characteristics 

分 类 号：Q94[生物学—植物学]