电热针辅助治疗慢性阻塞性肺疾病稳定期:随机对照试验  

Stable chronic obstructive pulmonary disease treated by adjunctive therapy of electrothermal acupuncture: a randomized controlled trial

作　　者：李珊[1] 夏玉卿[2] 王海箭[2] 来薛[1] 吴蔚[1] LI Shan;XIA Yuqing;WANG Haijian;LAI Xue;WU Wei(Department of Respiration,Wangjing Hospital of China Academy of Chinese Medical Sciences,Beijing 100102,China;Clinic of Electrothermal Acupuncture,Wangjing Hospital of China Academy of Chinese Medical Sciences,Beijing 100102,China)

机构地区：[1]中国中医科学院望京医院呼吸科,北京100102 [2]中国中医科学院望京医院电热针门诊,北京100102

出　　处：《中国针灸》2024年第10期1125-1129,共5页Chinese Acupuncture & Moxibustion

基　　金：北京市中医药科技发展资金项目:JJ2018-94;北京中医药薪火传承“3+3”工程项目:2021-SZ-B-43。

摘　　要：目的:评估电热针辅助治疗慢性阻塞性肺疾病(COPD)稳定期患者的疗效及安全性。方法:将66例COPD稳定期患者随机分为观察组和对照组,各33例。对照组应用支气管舒张剂气道吸入联合呼吸训练治疗4周;观察组在对照组基础上使用电热针治疗,主穴取双侧曲池、足三里、三阴交,以电热针施治,配穴结合不同证型取穴,以毫针施治,隔日1次,每周3次,共治疗4周。比较两组患者治疗前后肺功能[第1秒用力呼气容积(FEV1)、用力肺活量(FVC)、FEV1/FVC、肺一氧化碳弥散量(DLCO)占预计值百分比(DLCO%)]、6分钟步行距离(6MWD)、慢性阻塞性肺疾病评估测试(CAT)评分,随访1年记录两组患者急性加重情况,并评定电热针治疗安全性。结果:与治疗前比较,治疗后两组患者FEV1、FVC、FEV1/FVC、DLCO%、6MWD升高(P<0.01,P<0.05),CAT评分降低(P<0.01);观察组FEV1、FVC、FEV1/FVC、6MWD高于对照组(P<0.05),CAT评分低于对照组(P<0.05)。随访1年观察组急性加重患者例数少于对照组(P<0.05)。观察组未出现治疗相关不良反应。结论:在支气管舒张剂气道吸入联合呼吸训练的基础上,应用电热针治疗可以安全有效地改善COPD稳定期患者的肺功能,增强运动能力,并减少急性加重次数。Objective To assess the effect and safety of electrothermal acupuncture in adjunctive treatment of stable chronic obstructive pulmonary disease(COPD) in patients. Methods Sixty-six stable COPD patients were randomly divided into an observation group and a control group, with 33 cases in each group. The patients in the control group were treated with bronchodilator inhalation combined with respiratory training for 4 weeks. In the observation group, on the basis of the treatment as the control group, electrothermal acupuncture was delivered at bilateral Quchi(LI 11), Zusanli(ST 36) and Sanyinjiao(SP 6),and the conventional filiform needling was operated at the supplementary acupoints selected according to the individual syndrome. The interventions in the observation group were given once every two days, 3 treatments a week, for consecutive 4 weeks. Before and after treatment completion, the lung functions(forced expiratory volume in the first second [FEV1], forced vital capacity [FVC], FEV1/FVC and the percentage of diffusing capacity of the lungs for carbon monoxide [DLCO%]), 6 min walking distance(6MWD) and the score of COPD assessment test(CAT) were compared between the two groups. The attacks of acute exacerbation were recorded in 1-year follow-up visit in the two groups and the safety of electrothermal acupuncture was evaluated. Results After treatment, FEV1, FVC, FEV1/FVC, DLCO% and 6MWD were increased(P<0.01, P<0.05), and CAT scores were decreased(P<0.01) in the two groups compared with those before treatment. FEV1, FVC, FEV1/FVC and 6MWD were higher and CAT score was lower in the observation group when compared with those of the control group(P<0.05).In the 1-year follow-up visit, the cases of acute exacerbation in the observation group were fewer than that in the control group(P<0.05). There were no treatment-related adverse reactions in the observation group. Conclusion On the basis of bronchodilator inhalation and respiratory training, electrothermal acupuncture can ameliorate the lung function, strength

关 键 词：慢性阻塞性肺疾病 稳定期 电热针治疗 肺功能 生活质量 随机对照试验 

分 类 号：R563.9[医药卫生—呼吸系统]