ICP-MS法测定多刺绿绒蒿及9种藏药材中的无机元素  

To Determine the Content of Inorganic Elements in Meconopsis Horridula and Fifteen Kinds of Tibetan Medicine by ICP-MS Method

作　　者：周冰洁 刘永权 赵雪莲 戴先芝 任朝琴 Zhou Bingjie;Liu Yongquan;Zhao Xuelian;Dai Xianzhi;Ren Chaoqin(Aba Normal University,Abazhou 624000,China;Guangxi University,Nanning 530004,China)

机构地区：[1]阿坝师范学院,四川阿坝州624000 [2]广西大学,广西南宁530004

出　　处：《云南化工》2024年第10期140-143,共4页Yunnan Chemical Technology

基　　金：四川省自然科学基金(2023NSFSC0610);全国大学生创新训练项目(S2023106460026);阿坝师范学院学生科研项目(20222001320)。

摘　　要：为建立测定多刺绿绒蒿不同药用部位及9种藏药中无机元素含量的方法,采用微波消解法对样品进行初步处理,用电感耦合等离子体质谱(ICP-MS)法对多刺绿绒蒿全草、根、茎、叶、花、果实中的无机元素含量进行测定,同时还对9种藏药(柳叶风毛菊、兔儿草、黄花铁线莲、水柏枝、藏木香、红毛五加、麻花艽、藏红花、天竺黄)中15种无机元素(Mg、Al、Ca、Ti、V、Cr、Mn、Fe、Co、Ni、Cu、Sr、Sb、Ba、Pb)含量进行分析。各元素在其线性范围内相关性良好,R>0.9,RSD<5%。结果表明,多刺绿绒蒿含量较高的常量元素为Ca、Mg,微量元素有Fe、Al和Cr等,且不同药用部位的微量元素含量存在差异。9种藏药含量较高的常量元素均为Ca、Mg,微量元素在不同植株中含量不同。通过对多刺绿绒蒿药用部位含量的分析,为多刺绿绒蒿生产质量控制及质量评价、探究其药效和药性等奠定了研究基础,同时为9种藏药全草无机元素含量提供参考。In order to establish a method for the determination of 15 inorganic elements in different parts of Meconopsis horridula and 9 kinds of Tibetan medicine,the contents of inorganic elements in different medicinal parts of Meconopsis horridula and 9 kinds of Tibetan medicine were determined.In this study,the samples were preliminarily treated by microwave digestion,and the contents of inorganic elements in the whole grass,roots,stems,leaves,flowers and fruits of Meconopsis horridula were determined by inductively coupled plasma mass spectrometry(ICP-MS).At the same time,the contents of 15 inorganic elements(Mg,Al,Ca,Ti,V,Cr,Mn,Fe,Co,Ni,Cu,Sr,Sb,Ba,Pb)in 9 kinds of Tibetan medicines(Saussurea salicifolia,Lagotis,Clematis tinctoria,Sabina chinensis,Aucklandialappa,Eleutherococcusgiraldii,Gentiana straminea,Crocus sativus L.,Pelargonium gigantean)were also analyzed.The correlation of each element in its linear range was good(R>0.9),RSD<5%.The results showed that the major elements with high content were Ca and Mg,and the trace elements were Fe,Al and Cr,and the content of trace elements in different medicinal parts was different.The major elements with high content of nine Tibetan medicines are Ca and Mg,and the content of trace elements is different in different plants.Through the analysis of the content of medicinal parts of Meconopsis horridula,it laid a research foundation for the production quality control and quality evaluation of Meconopsis horridula,and explored its efficacy and medicinal properties.At the same time,it provided a reference for the content of inorganic elements in the whole grass of 9 Tibetan medicines.

关 键 词：多刺绿绒蒿 藏药材 无机元素含量 电感耦合等离子体质谱法 

分 类 号：R282[医药卫生—中药学] R284[医药卫生—中医学]