氨基化明胶海绵的制备及其止血性能研究  

Preparation of aminated gelatin sponges and study on their hemostatic properties

作　　者：朱雨荷 黄芳艳 巨晓洁[1,2] ZHU Yu-he;HUANG Fang-yan;JU Xiao-jie(School of Chemical Engineering,Sichuan University,Chengdu 610065,China;State Key Laboratory of Polymer Materials Engineering,Sichuan University,Chengdu 610065,China)

机构地区：[1]四川大学化学工程学院,四川成都610065 [2]四川大学高分子材料工程国家重点实验室,四川成都610065

出　　处：《现代化工》2024年第S02期94-98,共5页Modern Chemical Industry

基　　金：国家自然科学基金项目(21991101)。

摘　　要：对明胶进行氨基化改性,同时用京尼平和单宁酸作为交联剂进行交联反应,然后冷冻干燥得到了氨基化明胶海绵。结果表明,该海绵具有丰富的孔状结构以及快速吸水能力,同时能够通过静电相互作用增强与血细胞间的结合能力,使其具有优异的止血性能,为快速止血材料的制备提供了新方法。To prepare hemostatic materials with excellent hemostatic performance,the gelatin is modified through amination,and then cross-linked with tannic acid and genipin as cross-linking agents,followed by freeze-drying to obtain an aminated gelatin sponge.This sponge has a rich porous structure and rapid water absorption capacity.It can also enhance the binding ability with blood cells through electrostatic interactions,exhibiting excellent hemostatic performance,thus providing a new method for the preparation of rapid hemostatic materials.

关 键 词：止血海绵 氨基化明胶 京尼平 单宁酸 止血材料 

分 类 号：TQ431.3[化学工程]