Biodegradation of Crystalline Chitin:A Review of Recent Advancement,Challenges,and Future Study Directions  

作　　者：SONG Jianlin SU Haipeng SUN Jianan MAO Xiangzhao 

机构地区：[1]Sanya Institute of Oceanography,Ocean University of China,Sanya 572000,China [2]State Key Laboratory of Marine Food Processing and Safety Control,College of Food Science and Engineering,Ocean University of China,Qingdao 266404,China [3]Qingdao Key Laboratory of Food Biotechnology,Qingdao 266404,China [4]Key Laboratory of Biological Processing of Aquatic Products,China National Light Industry,Qingdao 266404,China [5]Laboratory for Marine Drugs and Bioproducts of Laoshan Laboratory,Qingdao 266237,China

出　　处：《Journal of Ocean University of China》2024年第5期1319-1328,共10页中国海洋大学学报（英文版）

基　　金：supported by the National Key Research and Development Program of China(No.2023YFD2401504);the National Natural Science Foundation of China(Nos.U21A20271,32225039);the Key R&D Program of Shandong Province(No.2022TZXD001);the Earmarked Fund for CARS(No.CARS-48);the Qingdao Shinan District Science and Technology Plan Project(No.2022-3-010-SW).

摘　　要：Chitin is the second most abundant renewable polysaccharide on Earth.The degradation of chitin into soluble and bioactive N-acetyl chitooligosaccharides(NCOSs)and N-acetyl-D-glucosamine(GlcNAc)has emerged as a pivotal step in the efficient and sustainable utilization of chitin resources.However,because of its dense structure,high crystallinity,and poor solubility,chitin typically needs pretreatment via chemical,physical,and other methods before enzymatic conversion to enhance the accessibility between substrates and enzyme molecules.Consequently,there has been considerable interest in exploring the direct biological degradation of crystalline chitin as a cost-effective and environment-friendly technology.This review endeavors to present several biological methods for the direct degradation of chitin.We primarily focused on the importance of chitinase containing chitin-binding domain(CBD).Additionally,various modification strategies for increasing the degradation efficiency of crystalline chitin were introduced.Subsequently,the review systematically elucidated critical components of multi-enzyme catalytic systems,highlighting their potential for chitin degradation.Furthermore,the application of microorganisms in the degradation of crystalline chitin was also discussed.The insights in this review contribute to the explorations and investigations of enzymatic and microbial approaches for the direct degradation of crystalline chitin,thereby fostering advancements in biomass conversion.

关 键 词：crystalline chitin CHITINASE biological degradation engineering MICROORGANISMS 

分 类 号：O636[理学—高分子化学]