多b值弥散加权成像和磁共振增强扫描在评估胶质瘤术后复发及假性进展中的价值  

Value of multiple b-value diffusion weighted imaging and MRI-enhanced scanning in assessing recurrence and pseudoprogression of glioma after surgery

作　　者：周琴[1] 方祥勇 ZHOU Qin;FANG Xiangyong(Department of Radiology,The Affiliated Dazu's Hospital of Chongqing Medical University,Chongqing 402360,China)

机构地区：[1]重庆医科大学附属大足医院放射科,重庆402360

出　　处：《影像研究与医学应用》2024年第20期38-40,共3页Journal of Imaging Research and Medical Applications

摘　　要：目的:分析多b值弥散加权成像(DWI)和磁共振增强扫描在评估胶质瘤术后复发及假性进展中的价值。方法:回顾性收集2023年7月—2024年1月重庆医科大学附属大足医院收治的胶质瘤术后患者46例的病历资料,所有患者均接受磁共振成像(MRI)与多b值DWI检查,分析多b值DWI和磁共振增强扫描对胶质瘤术后复发及假性进展的诊断价值;并进一步分析参数表观弥散系数(ADC)与分布弥散系数(DDC)的相关性。结果:本研究纳入46例患者中明确检出胶质瘤复发26例,假性进展20例;胶质瘤复发组ADC、D、f、DDC、α值低于假性进展组,D^(*)值高于假性进展组,差异有统计学意义(P<0.05);绘制ROC曲线,结果显示,ADC、D、D^(*)、f、DDC与α值的AUC均>0.7,具有一定诊断价值;采用双变量Pearson相关性检验分析发现,DDC与ADC值之间呈正相关(P<0.05)。结论:多b值DWI和磁共振增强扫描在胶质瘤术后复发及假性进展鉴别诊断中具有较高价值,可为临床诊断提供可靠的诊断依据。Objective To analyze the value of multi-b-value diffusion weighted imaging(DWI)and MRI-enhanced scanning in the assessment of postoperative recurrence and pseudoprogression of glioma.Methods 46 postoperative glioma patients admitted to the Affiliated Dazu's Hospital of Chongqing Medical University during July 2023 to January 2024 were retrospectively collected,and all the patients were examined by magnetic resonance imaging(MRI),multi-b-value DWI.The diagnostic value of multiple b-value DWI and enhanced MRI scan for glioma was analyzed,and the correlation between apparent diffusion coefficient(ADC)and distributed diffusion coefficient(DDC)was further analyzed.Results Forty-six patients were included in this study,and 26 cases of glioma recurrence and 20 cases of pseudoprogression were clearly detected;ADC,D,f,DDC,andαvalues were lower than those of the pseudoprogression group in the glioma recurrence group,and D^(*)value was higher than those of the pseudoprogression group(P<0.05);ROC curves were plotted,and the results showed that the AUC of ADC,D,D^(*),f,DDC andαvalues were all>0.7,which has certain diagnostic value;the bivariate Pearson correlation test was used to analyze the positive correlation between DDC and ADC values(P<0.05).Conclusion Multi-b-value DWI and MRI-enhanced scanning have high value in the differential diagnosis of postoperative recurrence and pseudoprogression of gliomas,and can provide a reliable diagnostic basis for clinical diagnosis.

关 键 词：胶质瘤复发 假性进展 多b值弥散加权成像 诊断价值 

分 类 号：R445.2[医药卫生—影像医学与核医学]