负压辅助愈合治疗系统对糖尿病足溃疡患者创面愈合及疼痛程度的影响  

Impact of Vacuum-assisted Closure Therapy on Wound Healing and Pain Levels in Patients with Diabetic Foot Ulcers

作　　者：李翠洁 殷东京[1] 孙记燕[1] LI Cuijie;YIN Dongjing;SUN Jiyan(Department of Burns and Plastic Surgery,Nantong Third People's Hospital(Nantong Third Hospital Affiliated to Nan-tong University),Nantong 226000,Jiangsu,China)

机构地区：[1]南通市第三人民医院(南通大学附属南通第三医院)烧伤整形外科,江苏南通226000

出　　处：《糖尿病新世界》2024年第14期180-183,共4页Diabetes New World

摘　　要：目的 探讨负压辅助愈合治疗系统对糖尿病足溃疡患者创面愈合及疼痛程度的影响。方法 选取2022年2月—2024年2月南通市第三人民医院收治的80例糖尿病足溃疡患者为研究对象,按照治疗方法的不同分为对照组和观察组,每组40例。对照组接受常规创面处理,观察组在对照组基础上使用负压辅助愈合治疗系统。比较两组创面愈合效果、血液炎症指标、视觉模拟法(Visual Analogue Scale, VAS)评分。结果 治疗后,观察组创面深度和溃疡面积均小于对照组,差异有统计学意义(P均<0.05)。治疗后,观察组白细胞计数、中性粒细胞比率、C反应蛋白、降钙素原水平均低于对照组,差异有统计学意义(P均<0.05)。治疗后,观察组VAS评分低于对照组,差异有统计学意义(P<0.05)。结论 负压辅助愈合治疗系统能促进糖尿病足溃疡患者的创面愈合,改善血液炎症指标,并有效降低疼痛程度,为糖尿病足溃疡的综合治疗提供了重要的临床依据。Objective To investigate the effect of vacuum-assisted closure therapy on wound healing and pain degree in patients with diabetic foot ulcers.Methods A total of 80 patients with diabetic foot ulcers admitted to Nantong Third People's Hospital from February 2022 to February 2024 were selected as the research objects.According to dif-ferent treatment methods,they were divided into control group and observation group,with 40 cases in each group.The control group received routine wound treatment,and the observation group used vacuum-assisted closure therapy on the basis of the control group.The wound healing effect,blood inflammation indexes and Visual Analogue Scale(VAS)score were compared between the two groups.Results After treatment,the wound depth and ulcer area of the observation group were smaller than those of the control group,and the differences were statistically significant(both P<0.05).After treatment,the white blood cell count,neutrophil ratio,C-reactive protein and procalcitonin in the observa-tion group were lower than those in the control group,and the differences were statistically significant(all P<0.05).Af-ter treatment,the VAS score of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Vacuum-assisted closure therapy can promote wound healing in patients with diabetic foot ulcers,improve blood inflammatory indicators,and effectively reduce the degree of pain,which pro-vides an important clinical basis for the comprehensive treatment of diabetic foot ulcers.

关 键 词：负压辅助愈合治疗系统 糖尿病足溃疡 创面愈合 

分 类 号：R587.1[医药卫生—内分泌]