持续气道正压通气和双水平气道正压通气治疗射血分数降低型急性心力衰竭患者的疗效对比  

Comparison of Continuous Positive Airway Pressure Ventilation and Bi level Positive Airway Pressure Ventilation in the Treatment of Patients with Acute Heart Failure with Decreased Ejection Fraction

作　　者：郑李龙 何晃养 严家兴 李泽茂 梁瑜 刘歆 刘维强 张丽荣 ZHENG Lilong;HE Huangyang;YAN Jiaxing;LI Zemao;LIANG Yu;LIU Xin;LIU Weiqiang;ZHANG Lirong(Emergency Department,Xinxing County People's Hospital,Xinxing 527400,Guangdong,China;Cardiology De-partment,Xinxing County People's Hospital,Xinxing 527400,Guangdong,China)

机构地区：[1]新兴县人民医院急诊科,广东新兴527400 [2]新兴县人民医院心内科,广东新兴527400

出　　处：《系统医学》2024年第17期16-19,共4页Systems Medicine

基　　金：云浮市医学科学技术研究项目(2022B083)。

摘　　要：目的探讨持续气道正压通气(continuous positive airway pressure,CPAP)和双水平气道正压通气(bi-level positive airway pressure ventilation,BiPAP)对射血分数降低型急性心力衰竭(acute heart failure,AHF)患者的治疗效果。方法非随机选取2022年6月—2023年12月新兴县人民医院收治的58例AHF伴射血分数降低型AHF患者为研究对象,按照治疗方法不同分为CPAP组和BiPAP组,各29例。比较两组治疗前后呼吸功能指标和血流动力学指标。结果BiPAP组治疗后动脉氧分压高于CPAP组[(93.65±7.48)mmHg vs(89.36±7.45)mmHg],动脉二氧化碳分压低于CPAP组[(35.06±4.01)mmHg vs(39.54±3.68)mmHg],差异有统计学意义(t=2.188、4.433,P均<0.05)。治疗后,两组全心舒张末期容积指数、血管外肺水指数均随时间的推移明显降低,与治疗前相比,差异有统计学意义(P均<0.05)。但两组间上述指标对比,差异无统计学意义(P均>0.05)。结论与CPAP相比,BiPAP可更好地改善AHF患者的呼吸功能,二者均不会对患者的血流动力学产生明显的不良影响。Objective To investigate the therapeutic effects of continuous positive airway pressure(CPAP)and bi-level positive airway pressure ventilation(BiPAP)in patients with acute heart failure with reduced ejection fraction acute heart failure(AHF)patients with reduced ejection fraction.Methods Fifty-eight patients with AHF accompa-nied by decreased ejection fraction admitted to Xinxing County People's Hospital from June 2022 to December 2023 were non-randomly selected as the study subjects.They were divided into CPAP group and BiPAP group according to different treatment methods,with twenty-nine patients in each group.Compare the respiratory function indicators and hemodynamic indicators between two groups before and after treatment.Results After treatment,the arterial oxygen partial pressure in the BiPAP group was higher than that in the CPAP group[(93.65±7.48)mmHg vs(89.36±7.45)mmHg],the arterial carbon dioxide partial pressure was lower than that in the CPAP group[(35.06±4.01)mmHg vs(39.54±3.68)mmHg],the differences were statistically significant(t=2.188,4.433,both P<0.05).After treatment,both groups showed a significant decrease in end diastolic volume index and extravascular lung water index over time,the differences were statistically significant compared to before treatment(both P<0.05).However,there was no statisti-cally significant difference in the above indicators between the two groups(all P>0.05).Conclusion Compared with CPAP,BiPAP can improve the respiratory function of patients with acute heart failure,reduce the ejaculation fraction,and has no significant adverse effect on the hemodynamics of patients.

关 键 词：持续气道正压通气 双水平气道正压通气 射血分数降低型 急性心衰 疗效分析 

分 类 号：R541.61[医药卫生—心血管疾病]