重复经颅磁刺激与无抽搐电休克治疗首发抑郁症的临床效果分析  

Analysis of the Clinical Effects of Repetitive TMS with No Convulsive Elec⁃troshock for First Episode Depression

作　　者：刘锡亮[1] 姜丽丽[2] 王欣[1] 李钰 LIU Xiiang;JIANG Lii;WANG Xin;LI Yu(Special Inspection Department,Qingdao Mental Health Center,Shangdong Province,Qingdao 266000,Shandong,China;Oncology Department,Qingdao Central Hospital Affiliated to Qingdao University,Shangdong Province,Qing-dao Central Hospital,Qingdao 266000,Shandong,China)

机构地区：[1]山东省青岛市精神卫生中心特检科,山东青岛266000 [2]山东省青岛大学附属青岛市中心医院,青岛市肿瘤医院肿瘤科,山东青岛266000

出　　处：《系统医学》2024年第17期34-37,共4页Systems Medicine

摘　　要：目的研究分析首发抑郁症患者采用重复经颅磁刺激、无抽搐电休克治疗的临床疗效。方法非随机选取2022年1—12月山东省青岛市精神卫生中心收治的80例首发抑郁症患者为研究对象,根据治疗方法不同分为常规组、观察组,各40例。常规组采取无抽搐电休克治疗,观察组采取重复经颅磁刺激+无抽搐电休克治疗。对比两组患者的抑郁病情、认知功能和不良反应发生情况。结果治疗后,观察组各时间点的汉密尔顿抑郁量表评分和各项威斯康星卡片分类试验得分均优于常规组,差异有统计学意义(P均<0.05)。观察组不良反应发生率为10.00%(4/40),与常规组的7.50%(3/40)对比,差异无统计学意义(χ^(2)=0.157,P>0.05)。结论采用重复经颅磁刺激与无抽搐电休克联合治疗首发抑郁症可有效促进患者病情改善。Objective To study and analyze the clinical efficacy of repeated transcranial magnetic stimulation and non convulsive electroconvulsive therapy in patients with first episode depression.Methods Eighty patients with primary depression admitted to the Qingdao Mental Health Center in Shandong Province from January to December 2022 were non-randomly selected as the research subjects.They were divided into a conventional group and an observation group,with forty patients in each group,according to different treatment methods.The conventional group received non convulsive electroconvulsive therapy,while the observation group received repeated transcranial magnetic stimula-tion plus non convulsive electroconvulsive therapy.Compare the depression status,cognitive function,and incidence of adverse reactions between two groups of patients.Results After treatment,the Hamilton Depression Scale scores and Wisconsin Card Sorting Test scores of the observation group at each time point were better than those of the con-trol group,and the differences were statistically significant(all P<0.05).The incidence of adverse reactions in the ob-servation group was 10.00%(4/40),which was not significantly different from the 7.50%(3/40)in the conventional group(χ^(2)=0.157,P>0.05).Conclusion The combination of repeated transcranial magnetic stimulation and non convul-sive electroconvulsive therapy can effectively promote the improvement of patients with primary depression.

关 键 词：重复经颅磁刺激 无抽搐电休克 首发抑郁症 治疗效果 

分 类 号：R4[医药卫生—临床医学]