布地奈德雾化吸入联合高频振荡通气治疗新生儿呼吸窘迫综合征的效果观察  

Observation on the Effect of Budesonide Atomization Inhalation Combined with High Frequency Oscillatory Ventilation in the Treatment of Neonatal Respiratory Distress Syndrome

作　　者：梁惠如 彭二扣 宋瑞 LIANG Huiru;PENG Erkou;SONG Rui(Neonatal Intensive Care Unit,Shangqiu First People's Hospital,Shangqiu 476000,China;Pediatric Intensive Care Unit,Shangqiu First People's Hospital,Shangqiu 476000,China)

机构地区：[1]商丘市第一人民医院新生儿重症监护室,河南商丘476000 [2]商丘市第一人民医院儿童重症监护室,河南商丘476000

出　　处：《临床医学工程》2024年第10期1171-1172,共2页Clinical Medicine & Engineering

摘　　要：目的观察布地奈德雾化吸入联合高频振荡通气(HFOV)治疗新生儿呼吸窘迫综合征(NRDS)的效果和安全性。方法68例NRDS患儿随机分为两组各34例。在常规治疗基础上,对照组采用布地奈德混悬液雾化吸入治疗,观察组采用布地奈德混悬液雾化吸入+HFOV治疗。比较两组的恢复情况、血气指标及并发症。结果观察组的通气、氧疗及住院时间均短于对照组,治疗期间的并发症总发生率低于对照组(P<0.05)。治疗1周后,观察组的PaO_(2)、pH值均高于对照组,PaCO_(2)低于对照组(P<0.05)。结论布地奈德雾化吸入联合HFOV治疗可有效调节NRDS患儿的血气指标,减少并发症的发生,加快患儿康复。Objective To observe the effect and safety of budesonide atomization inhalation combined with high frequency oscillatory ventilation(HFOV)in the treatment of neonatal respiratory distress syndrome(NRDS).Methods A total of 68 neonates with NRDS were randomly divided into two groups,with 34 cases in each group.On the basis of conventional treatment,the control group was treated with budesonide suspension atomization inhalation,and the observation group was treated with budesonide suspension atomization inhalation+HFOV.The recovery situation,blood gas indicators and complications were compared between the two groups.Results The ventilation time,oxygen therapy time and hospitalization time of the observation group were shorter than those of the control group,and the total incidence of complications during treatment was lower than that of the control group(P<0.05).After 1 week of treatment,PaO_(2) and pH value of the observation group were higher than those of the control group,and PaCO_(2) was lower than that of the control group(P<0.05).Conclusions Budesonide atomization inhalation combined with HFOV treatment can effectively regulate the blood gas indicators of neonates with NRDS,reduce the occurrence of complications,and accelerate the recovery of neonates.

关 键 词：布地奈德雾化吸入 高频振荡通气 新生儿呼吸窘迫综合征 

分 类 号：R725.6[医药卫生—儿科]