新生儿高胆红素血症需行换血治疗的临床分析  

Clinical analysis of requiring exchange blood therapy of the neonates with hyperbilirubinemia

作　　者：陆国琴 黄华飞[1] 祝峰 丁晓玲 张寅英[2] LU Guoqin;HUANG Huafei;ZHU Feng;DING Xiaoling;ZHANG Yinying(Department of Neonatal,Jiaxing Maternal and Child Health Care Hospital,Jiaxing 314000,CHINA)

机构地区：[1]嘉兴市妇幼保健院新生儿科,浙江314000 [2]嘉兴市妇幼保健院药剂科,浙江314000 [3]嘉兴市第二医院儿科

出　　处：《江苏医药》2024年第9期932-934,共3页Jiangsu Medical Journal

基　　金：浙江省医药卫生科技计划项目(2023KY1218)

摘　　要：目的 分析新生儿高胆红素血症需要行换血治疗的临床特征。方法 回顾性分析163例高胆红素血症新生儿(出生胎龄≥35周,出生日龄≤28d)的临床资料。根据光疗或换血治疗标准,其中行换血治疗50例(换血组),行光疗113例(光疗组)。比较两组临床和实验室血液指标,分析新生儿高胆红素血症需要行换血治疗的临床特征。结果 与光疗组比较,换血组患儿胎龄更大、入院时间更短及合并ABO溶血比例更高(P<0.05),且患儿WBC降低,而Hb和红细胞比积(Hct)升高(P<0.01)。结论 患儿胎龄更大、入院时间更短、合并ABO溶血及Hct更高为新生儿高胆红素血症需行换血治疗的临床特征。Objective To analyze the clinical characteristics of requiring exchange blood therapy in the neonates with hyperbilirubinemia.Methods The data of 163 neonates(gestational age≥35 weeks and birth age<28 days)with hyperbilirubinemia were analyzed.According to the standard of phototherapy or exchange blood therapy,50 cases were treated with exchange blood therapy in group A,and 113 cases were treated with phototherapy in group B.The clinical and laboratory blood indicators of the two groups were compared to analyze clinical characteristics of requiring exchange blood therapy in the neonates with hyperbilirubinemia.Results Compared with group B,group A had longer gestational age,shorter admission time and higher proportion of combined with ABO hemolysis(P<0.05),as well as lower WBC,but higher Hb and hematocrit(Hct)(P<0.01).Conclusion Older gestational age,shorter admission time,combined with ABO hemolysis and higher Hct were the clinical characteristics of requiring exchange blood therapy in the neonates with hyperbilirubinemia.

关 键 词：高胆红素血症 换血治疗 新生儿 

分 类 号：R722[医药卫生—儿科]