造血干细胞移植患者腹泻评估与管理的最佳证据总结  

Summary of best evidence for diarrhea assessment and management in hematopoietic stem cell transplantation patients

作　　者：毛小培[1] 徐敏[2] 张晓兰[3] 彭敏 程芳 沈王芳[1] 叶梦华 Mao Xiaopei;Xu Min;Zhang Xiaolan;Peng Min;Cheng Fang;Shen Wangfang;Ye Menghua(Department of Hematology,the First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine),Hangzhou 310003,China;Hospital Management Office,the First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine),Hangzhou 310003,China;Nursing Department,the First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine),Hangzhou 310003,China)

机构地区：[1]浙江中医药大学附属第一医院(浙江省中医院)血液科,杭州310003 [2]浙江中医药大学附属第一医院(浙江省中医院)医院管理办公室,杭州310003 [3]浙江中医药大学附属第一医院(浙江省中医院)护理部,杭州310003

出　　处：《中华现代护理杂志》2024年第30期4163-4170,共8页Chinese Journal of Modern Nursing

基　　金：浙江省中医药科技计划(2024ZL067);浙江省医药卫生科技计划(2024KY1224);浙江中医药大学科研项目(2023FSYYZQ09)。

摘　　要：目的检索、评价并总结国内外关于造血干细胞移植(HSCT)患者腹泻评估与管理的证据,为临床实践提供循证依据。方法根据"6S"模型系统检索国内外相关数据库和网站中与HSCT患者腹泻评估与管理相关的文献,包括指南、临床决策、推荐实践、证据总结、系统评价及专家共识,检索时限均为2013年1月1日—2023年11月30日。由7名研究者对文献进行筛选、质量评价、证据提取及汇总。结果共纳入15篇文献,其中指南4篇、临床决策3篇、推荐实践2篇,证据总结1篇、系统评价2篇、专家共识3篇。从多学科管理、危险因素管理、评估与监测、药物干预、饮食与营养管理、健康教育及日常管理7个方面汇总了31条证据。结论总结的HSCT患者腹泻评估与管理的最佳证据,可为临床实践提供参考,护理人员应结合患者实际,审慎地应用证据。Objective To retrieve,evaluate,and summarize evidence on the assessment and management of diarrhea in hematopoietic stem cell transplantation(HSCT)patients both domestically and internationally,providing evidence-based support for clinical practice.Methods According to the"6S"model,guidelines,clinical decisions,recommended practices,evidence summaries,systematic reviews,and expert consensus related to the assessment and management of diarrhea in HSCT patients were systematically retrieved from relevant databases and websites both domestically and internationally.The search period was from January 1,2013 to November 30,2023.Seven researchers conducted literature screening,quality evaluation,evidence extraction,and summarization.Results A total of 15 articles were included,including four guidelines,three clinical decisions,two recommended practices,one evidence summary,two systematic reviews,and three expert consensus.Thirty-one pieces of evidence were summarized from seven aspects of multidisciplinary management,risk factor management,assessment and monitoring,medication intervention,diet and nutrition management,health education,and daily management.Conclusions The best evidence for HSCT patient assessment and management summarized can provide reference for clinical practice,and nursing staff should carefully apply evidence based on the actual situation of patients.

关 键 词：造血干细胞移植 腹泻 护理评估 循证护理学 

分 类 号：R473[医药卫生—护理学]