宁夏地区孕产妇HBV检测及感染状况调查研究  

Research on HBV Detection and Infection Status of Pregnant Womenin Ningxia Region

作　　者：常晶晶 马睿 刘晓东 CHANG Jingjing;MA Rui;LIU Xiaodong(The First Hospital of Peking University,Ningxia Women and Children’s Hospital,Ningxia Hui Autonomous Region Maternal and Child Health Hospital,Yinchuan 750001,China)

机构地区：[1]北京大学第一医院宁夏妇女儿童医院,宁夏回族自治区妇幼保健院,银川750001

出　　处：《宁夏医科大学学报》2024年第8期836-839,共4页Journal of Ningxia Medical University

基　　金：宁夏自然科学基金项目(2021AAC03412)。

摘　　要：目的 了解2015—2021年宁夏地区孕产妇乙型肝炎病毒(HBV)检测及感染情况。方法 收集2015—2021年宁夏各助产机构发现并上报的感染HBV的孕产妇信息,通过预防艾滋病、梅毒和乙型肝炎母婴传播信息管理系统收集相关数据,并分析宁夏地区孕产妇HBV检测率、检测时期和HBV表面抗原(HBsAg)阳性率及其分布特征。结果 2015—2021年宁夏孕产妇HBV检测率99.95%,孕期检测率从69.11%上升至98.13%。累计648 360例孕产妇接受了HBV检测,报告HBsAg阳性孕产妇24 600例,HBsAg阳性率3.79%。24 600例HBsAg阳性孕产妇中,4 847例(19.70%)为仅产时接受检测。孕产妇孕期HBsAg阳性率呈逐年上升趋势,仅产时HBsAg阳性率呈逐年下降趋势,且2015—2019年孕产妇仅产时HBsAg阳性率均高于同期孕产妇孕期HBsAg阳性率。此外,2021年报告2 435例HBV感染孕产妇感染模式,14~<25岁组以模式1感染为主,25~<35岁组、35~<47岁组均以模式2感染为主。结论 2015—2021年宁夏地区孕产妇HBV检测率保持较高水平,孕期检测率显著上升,但仍存在一定比例的产时检测,需进一步采取措施促进孕产妇孕期尽早接受HBV检测,同时加强HBV感染孕产妇疾病监测管理。Objective To understand the status of maternal testing,detection,and trends of hepatitis B virus(HBV)infection among pregnant women in Ningxia region 2015—2021.Methods Data were collected from the monthly work report on maternal HBV testings and the case-reporting records of HBV-positive pregnant women,from the National Management Infogam System of China’s Prevention of Mother-to-child transmission of HIV,syphilis,and HBV Program.A descriptive method was applied to show both the maternal HBV and predelivery HBV testing rates and maternal HBsAg positive rates as well as the distribution between 2015 and 2021.Results 2015—2021,maternal HBV test rates were nearly 99.95%,and predelivery maternal HBV testing increased from 69.11%to 98.13%.A total of 24600 HBV-positives were detected from 648360 pregnant,with the HBsAg positives rate as 3.79%.Among 24600 HBsAg positive pregnant women,4847(19.70%)of them were tested at labor.The predelivery maternal HBsAg positive rates increased yearly,and maternal HBsAg positive rates at labor reduced yearly.2015—2019,the maternal HBsAg positive rate at labor was higher than that in the pregnant women who received HBV test predelivery.Among the reported 2435 HBsAg positives pregnant women,the first pattern of infection was predominant in the 14-<25 age group.The second pattern of infection was predominant in the 25-<35 and 35-<47 age groups.Conclusion 2015—2021,the maternal HBV test rates was at a high level,predelivery maternal HBV testing increased yearly,but the maternal HBV test rates at labor still existed.We need to take measures to promote early HBV testing during pregnancy,and strengthen disease surveillance and management.

关 键 词：孕产妇 乙型肝炎 检测率 阳性率 

分 类 号：R512.62[医药卫生—内科学]