泪腺突出度联合磁共振脂肪定量分析在甲状腺相关性眼病诊断中的价值  

The diagnostic value of lacrimal gland prominence combined with MRI fat quantitative analysis in thyroid-associated ophthalmopathy

作　　者：黄红艳[1] 王沁 黄继[3] 温佶俐[4] 华建军[1] 潘江峰[1] HUANG Hongyan;WANG Qin;HUANG Ji(Department of Radiology,Jinhua Municipal Central Hospital,Jinhua 321000,China)

机构地区：[1]金华市中心医院医学影像科,浙江金华321000 [2]金华市中心医院内分泌科,浙江金华321000 [3]金华市中心医院超声医学科,浙江金华321000 [4]金华市中心医院眼科,浙江金华321000

出　　处：《全科医学临床与教育》2024年第10期874-877,共4页Clinical Education of General Practice

基　　金：金华市科技局计划项目(2021-4-023);浙江省医药卫生科技计划项目(2023KY1282)。

摘　　要：目的探讨泪腺突出度和磁共振脂肪定量分析(IDEAL-IQ)在甲状腺相关性眼病(TAO)诊断中的价值。方法回顾性分析38例TAO患者(TAO组)和38例健康志愿者(对照组)的临床资料。通过测量泪腺突出度、脂肪分数(FF)及相对脂肪分数(rFF),比较组间的差异,并采用受试者工作特征(ROC)曲线分析泪腺突出度、FF、rFF单一检测和联合检测对TAO的诊断效能。结果TAO组泪腺突出度、FF和rFF均大于对照组(t分别=8.18、6.10,Z=-5.66,P均<0.05),泪腺突出度联合FF诊断TAO时,AUC最大,为0.88,特异度90.80%,灵敏度73.70%。结论TAO患者的泪腺突出度及脂肪含量大于对照组,泪腺突出度联合FF有助于TAO患者的诊断,具有较高的临床价值。Objective To investigate the value of lacrimal gland prominence and MRI fat quantitative analysis(IDE-AL-IQ)in the diagnosis of thyroid associated ophthalmopathy(TAO).Methods Clinical datas of 38 TAO patients(TAO group)and 38 healthy volunteers(control group)were retrospectively analyzed.Lacrimal gland prominence,fat fraction(FF)and relative fat fraction(rFF)were measured to analyze the differences between two groups.The receiver operating characteristic(ROC)curve was used to analyze the diagnostic efficacy of lacrimal gland protrusion,FF,rFF single and combined tests on TAO.Results The lacrimal gland prominence,FF and rFF in TAO group were higher than those in control group(t=8.18,6.10,Z=-5.66,P<0.05),The AUC of lacrimal gland prominence combined with FF for diagnosing TAO was 0.88,specificity was 90.80%,sensitivity was 73.70%.Conclusion The lacrimal gland prom-inence and FF of TAO patients are higher than those of control group.The combination of lacrimal gland prominence and FF is helpful for the diagnosis of TAO patients with high clinical value.

关 键 词：脂肪定量 脂肪分数 甲状腺相关性眼病 泪腺 

分 类 号：R581[医药卫生—内分泌] R771.3[医药卫生—内科学]