藏医治疗便秘症方剂组方配伍规律研究  

Study on the Compatibility of Prescriptions for the Treatment of Constipation in Tibetan Medicine

作　　者：边巴次仁 次旦平措 巴桑德吉 贡布 边巴顿珠 白玛拉宗 旦增央金 色珍 德吉白珍 Bianba Ciren;Cidan Pingcuo;Basang Deji;Gongbu;Bianba Dunzhu;Baima Lazong;Danzeng Yangjin;Sezhen;Deji Baizhen(Xizang Autonomous Region Tibetan Hospital(Xizang Autonomous Region Tibetan Medicine Research Institute),Lhasa 850000,China)

机构地区：[1]西藏自治区藏医院(西藏自治区藏医药研究院),拉萨850000

出　　处：《西藏科技》2024年第9期66-72,共7页Xizang Science And Technology

基　　金：西藏自治区科技厅2022年基地与人才项目;2023年中央对地方转移支付资金(中医药事业传承与发展)重点支持项目。

摘　　要：目的 该研究旨在通过数据挖掘技术,探索藏医治疗便秘症的用药规律,以期为藏药方剂的开发和利用提供理论依据。方法 采用Excel透视表对藏医方剂数据进行预处理,进而利用SPSS Modeler 18进行数据挖掘,并通过Gephi 0.10构建复杂网络以可视化藏医治疗便秘症的方剂关系。研究数据来源于《四部医典》《实用红卷》等藏医药经典中记载的便秘症治疗方剂。利用关联规则等数据挖掘技术分析常用药物、组方规律及核心药物组合。结果 共整理并分析了62首针对不同病因(隆、赤巴、培根、外伤、虫等)引起的便秘方剂。在全部方剂中,药物总出现频次达214次,其中32味药物的使用频次超过2次。高频药物包括碱花、诃子和大黄,其出现频率依次为13.55%、11.21%和9.81%.此外,研究发现常用药物组合包括大黄-诃子、大黄-碱花、诃子-碱花等。结论 本研究的数据挖掘结果表明,藏医治疗便秘症的核心药物主要是具有降“隆”、平“赤巴”功效的药物。常见的药物配伍包括大黄-诃子、大黄-碱花等。该研究结果揭示了藏医治疗便秘症的用药特征和配伍规律,为临床用药提供了科学依据,并为藏药新方剂的研发与创新提供了数据支撑。Objective The purpose of this study was to explore the medication rules of Tibetan medicine for the treatment of constipation through data mining techniques,in order to provide a theoretical basis for the development and utilization of Tibetan medicine prescriptions.Method The study applies Excel pivot tables for preprocessing Ti-betan medicine prescription data,followed by data mining through SPSS Modeler 18,and a complex network was constructed by Gephi 0.10 to visualize the relationship of prescriptions for constipation treatment in Tibetan medi-cine.The research data were sourced from the prescriptions for the treatment of constipation recorded in Tibetan med-icine classics such as the Four Medical Tantras and Practical Red Volume,.Data mining techniques such as associa-tion rules were applied to analyze commonly used drugs,formulation rules and core drug combinations.Results A to-tal of 62 constipation formulas for different etiologies(such as Lung,Tripa,Bekan,trauma,insects,etc.)were sorted out and analyzed.Among all the prescriptions,the total frequency of the drug was 214 times,of which 32 durgs were used more than twice.The most frequently used drugs included alkali flowers,Terminalia chebula,and rhubarb,with frequencies of 13.55%,11.21%and 9.81%respectively.Conclusion The data mining results of this study indicate that the core medications for treating constipation in Tibetan medicine are primarily those with the efficacy of reduc-ing"Lung"and balancing"Chiba".Commonly used medication combinations include rhubarb-Terminalia chebula and rhubarb-alkali flowers.The results of this study reveal the medication characteristics and compatibility patterns for treating constipation in Tibetan medicine,providing a scientific basis for clinical medication and data support for the research and development of new Tibetan medicine formulas.

关 键 词：藏医 便秘症 数据挖掘 复杂网络分析 方剂 规律 

分 类 号：R29[医药卫生—民族医学]