Atypical artificial cells:Novel biomimetic materials for combating cancer  

作　　者：Zhao-yang Ren Qian-qian Wan Yi-na Zhu Ling Li Kai-yan Wang Fei Zhao Kai Jiao Michelle Tang Franklin Tay Mei-chen Wan Li-na Niu 

机构地区：[1]Department of Prosthodontics,State Key Laboratory of Oral&Maxillofacial Reconstruction and Regeneration,National Clinical Research Center for Oral Diseases,Shaanxi Key Laboratory of Stomatology,School of Stomatology,The Fourth Military Medical University,Xi'an,Shaanxi,China [2]The Dental College of Georgia,Augusta University,Augusta,Georgia,USA

出　　处：《Interdisciplinary Materials》2024年第5期658-714,共57页交叉学科材料（英文）

基　　金：National Clinical Research Center for Oral Diseases,Grant/Award Number:LCA202004;National Natural Science Foundation of China,Grant/Award Numbers:82301043,82325012;Shaanxi Key Scientific and Technological Innovation Team,Grant/Award Number:2020TD-033。

摘　　要：The functional concept of using synthetic entities to supplement or replace certain functions or structures of biological cells is realized by the development of atypical artificial cells using a bottom-up approach.Tremendous progress has been achieved over the past 5 years that focuses on the therapeutic applications of atypical artificial cells,especially in the anticancer arena.Artificial cell-based anticancer strategies have demon-strated eminent advantages over conventional anticancer tactics,with excellent biocompatibility and targeting capability.The present review commences with introducing the constructing principles and classification of artificial cells.Artificial cell-based applications in cancer prophylaxis,diagnosis,and treatment are subsequently highlighted.These stimulating outcomes may inspire the development of next-generation anticancer ther-apeutic strategies.

关 键 词：atypical artificial cells bottom-up assembly cancer diagnosis cancer therapeutics NANOMEDICINE 

分 类 号：R318.08[医药卫生—生物医学工程]