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作 者:叶丹妮 王林元[1] 费文婷 林清 严利依 杨斌睿 杜军 王淳 张建军 陈亮 YE Dan-ni;WANG Lin-yuan;FEI Wen-ting;LIN Qing;YAN Li-yi;YANG Bin-rui;DU Jun;WANG Chun;ZHANG Jian-jun;CHEN Liang(School of Chinese Materia Medica,Beijing University of Chinese Medicine,Bejing 102488,China;School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 102488,China;Central College,New Westminster V3M3P1,Canada;Amway(Shanghai)Technology Development Co.,Ltd.,Shanghai 201203,China)
机构地区:[1]北京中医药大学中药学院,北京102488 [2]北京中医药大学中医学院,北京102488 [3]Central College,New Westminster V3M3P1 [4]安利(上海)科技发展有限公司,上海201203
出 处:《中国中药杂志》2024年第18期5095-5101,共7页China Journal of Chinese Materia Medica
基 金:国家中医药管理局国际合作司中医药国际合作专项(0730-236132ZC0052/01~04,0730-236132ZC0054/01~03)。
摘 要:东革阿里Eurycoma longifolia Jack.为苦木科植物,在东南亚具有数百年药用历史,被称为“马来西亚人参”。其临床与药理研究成果丰富,功效明显多样,安全性高,具有作为新的中药品种引入的条件和优势,市场开发价值很大。目前东革阿里在我国海南、广东等地已有种植,但尚未以药用资源引入应用,更无系统的中药药性研究。该文全面梳理并分析了东革阿里的应用历史、临床试验、生物活性、化学成分、安全性等研究,对其中药药性进行深入探讨。结果表明,东革阿里的药性为味甘,苦,辛,平;归肾、脾、肝经;功能主治为补肾益精,健脾益气,疏肝解郁;用于肾虚精亏,性欲淡漠,脾气虚弱,倦怠乏力,肝郁气滞。用法为水煎服,用量为每日服用2~10 g。该研究将促进东革阿里的“中药化”进程,有利于东革阿里与中药的配伍使用与产品开发,为东革阿里作为中药新资源的引入和国外参类药用植物的药性研究提供参考。Tongkat Ali(Eurycoma longifolia Jack.)is a medicinal plant of Simaroubaceae in Southeast Asia,with centuries of medicinal history.Rich clinical and pharmacological research results have been attained for this plant,which demonstrates diverse and definite effects and high safety,showcasing advantages and broad market prospects to be introduced as a new medicinal plant.Currently,E.longifolia is cultivated in Hainan and Guangdong in China.However,it has not been utilized for the medicinal purpose in China,and the systematic study on its traditional Chinese medicine(TCM)properties remains to be carried out.This paper comprehensively reviews and analyzes the application history,clinical trials,biological activities,chemical composition,and safety of Tongkat Ali and probes into its TCM properties.The results suggest that Tongkat Ali is sweet,bitter,pungent,and plain,with tropism to the kidney,spleen,and liver meridians.Tongkat Ali has the main functions of tonifying kidney and replenishing essence,invigorating spleen and replenishing Qi,and soothing liver and relieving depression.The clinical applications of Tongkat Ali encompass kidney essence deficiency,sex apathy,spleen Qi deficiency,fatigue,liver depression and Qi stagnation.The recommended dosage and usage of this medicine are 2-10 g daily and decoction with water,respectively.This study aims to facilitate the compatible use and product development of Tongkat Ali while providing reference for introducing it as a new TCM resource and studying the TCM properties of ginseng plants abroad.
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