糠酸莫米松鼻喷剂与西替利嗪滴剂治疗季节性过敏性鼻炎的临床效果分析  

Analysis of mometasone furoate nasal spray and cetirizine drops in treating seasonal allergicrhinitis

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作  者:毛向清 Mao Xiangqing(Department of Otolaryngology,Wulanchabu Central Hospital,Neimenggu,Wulanchabu,012000,China)

机构地区:[1]内蒙古乌兰察布市中心医院,内蒙古乌兰察布012000

出  处:《中国医学文摘(耳鼻咽喉科学)》2024年第5期149-152,共4页Chinese Medical Digest(Otorhinolaryngology)

摘  要:目的分析季节性过敏性鼻炎患者发病后采用糠酸莫米松鼻喷剂、西替利嗪滴剂治疗的效果。方法选取2023年1月-2024年1月接诊的季节性过敏性鼻炎患者86例作为研究对象,按随机抽签法分对照组、观察组,对照组行糠酸莫米松鼻喷剂治疗,观察组在对照组疗法上以西替利嗪滴剂治疗,比较两组患者的临床疗效及炎性因子、免疫功能及不良反应。结果观察组鼻炎治疗总有效率比对照组高,差异有统计学意义(p<0.05);干预前组间炎性指标对比无统计学意义(p>0.05),干预后观察组炎性因子水平比对照组低,p<0.05;治疗前两组患者免疫功能指标对比无显著差异(p>0.05),治疗后观察组免疫功能指标均高于对照组,p<0.05;观察组不良反应率与对照组相比差异不显著(p>0.05)。结论季节性过敏性鼻炎患者采取糠酸莫米松鼻喷剂联合西替利嗪滴剂治疗,有利于改善患者的鼻炎病情,调节患者的免疫功能,该给药方法的安全性高,具有应用价值。Objective To analyze the effect of nasal spray and cetirizine drops in patients with seasonal allergic rhinitis.Methods Select 86 cases of seasonal allergic rhinitis patients in January 2023-January 2024 as research object,control group,observation group,random draw group ometasone furoate nasal spray treatment,observation group with etirizine drops on the control group therapy,compare the clinical effcacy and inflammatory factors,immune function and adverse reactions of the two groups.Results The total response rate of rhinitis treatment was higher than that of the control group,the difference was statistically significant(p<0.05);the inflammatory index between the groups was not statistically significant(p>0.05),the observation group had lower levels than the control group,p<0.05;there was no significant difference between the two groups before treatment(p>0.05),and the immune function index was higher than the control group,p<0.05;the adverse response rate of the observation group was not significantly different from the control group(p>0.05).Conclusion The nasal spray combined with cetirizine drops for seasonal allergic rhinitis patients is beneficial to improving the rhinitis condition and regulating the immune function of patients.The administration method has high safety and application value.

关 键 词:西替利嗪滴剂 糠酸莫米松鼻喷剂 季节性过敏性鼻炎 疗效 炎性因子 

分 类 号:R47[医药卫生—护理学]

 

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