基于STM32F4+OV2640的HPV生物芯片阅读装置设计  

Design of HPV Biochip Reading Device Based on STM32F4+OV2640

作　　者：包琴 BAO Qin(Fujian Key Laboratory of Automotive Electronics and Electric Drive,Fujian University of Technology,Fuzhou,Fujian 350118,China)

机构地区：[1]福建理工大学福建省汽车电子与电驱动技术重点实验室,福建福州350118

出　　处：《自动化应用》2024年第19期144-146,153,共4页Automation Application

基　　金：福建省教育厅项目(JT180344,FJJKBK23-045,FBJY20230078);福建省工信厅技术创新重点攻关及产业化项目(2023XQ008);福建理工大学校级项目(GJ-ZD-23-02,KF-19-22001)。

摘　　要：定期开展HPV分型筛查,对提高妇女健康水平、预防宫颈癌发生的意义重大。为提高检测的自动化水平,减少人工介入和人为误判,设计HPV生物芯片阅读装置的重要性显著。采用STM32F429处理器结合OV2640CMOS传感器,配备M12镜头和可移动30 mm的载物台,可充分发挥可见光显色的TIB-23型HPV生物芯片的筛查优势。结果表明,所设计的HPV生物芯片阅读装置可直接使用HPV芯片杂交仪生化反应托盘,成功阅读四联装TIB-23型HPV生物芯片。该装置对提高HPV分型筛查自动化水平具有重要意义。Regular screening for HPV(Human Papilloma Virus,HPV)is of great significance in improving women′s health and preventing the occurrence of cervical cancer.In order to improve the automation of biochemical detection,reduce manual intervention and minimize the misjudgment,it is very important in designing an HPV biochip reading device.Based on this object,the application the STM32F429 processor combined with the OV2640 CMOS sensor,equipped with an M12 lens and a movable 30 mm stage,to achieve the HPV biochip reading device,which can fully leverage the screening advantages of visible and color TIB-23 HPV biochips.The test results show that the designed HPV biochip reading device can directly apply the biochemical reaction tray of HPV hybridization instrument,and successfully read the quadruple TIB-23 HPV biochips.This is of great significance for improving the automation level of HPV typing screening.

关 键 词：STM32F429处理器 HPV生物芯片 OV2640 CMOS传感器 图像传感器 阅读装置 

分 类 号：TH776[机械工程—仪器科学与技术]