个体化冠状动脉血管周围容积特征指数与冠心病的相关性  

Correlation between individualized coronary volumetric perivascular characterization index and coronary heart disease

作　　者：张艳春[1] 程丽 代岳 谢丽响 王浩[1] 刘欢 陈广义 ZHANG Yanchun;CHENG Li;DAI Yue;XIE Lixiang;WANG Hao;LIU Huan;CHEN Guangyi(Department of Radiology,Suining County People's Hospital,Xuzhou,Jiangsu Province 221200,China;Department of Radiology,the Affiliated Hospital of Xuzhou Medical University,Xuzhou,Jiangsu Province 221002,China)

机构地区：[1]睢宁县人民医院影像科,江苏徐州221200 [2]徐州医科大学附属医院影像科,江苏徐州221002

出　　处：《实用放射学杂志》2024年第9期1444-1448,共5页Journal of Practical Radiology

摘　　要：目的 探讨冠状动脉血管周围脂肪组织衰减指数(FAI_(PVAT))、血管周围容积特征指数(VPCI)与冠心病(CHD)的相关性.方法 选取在2周内同时行冠状动脉CT血管成像(CCTA)、冠状动脉造影(CAG)检查的112例患者,将患者按照冠状动脉管腔狭窄程度分为CHD组和对照组,按照斑块性质将患者分为钙化性斑块组、非钙化斑块组及混合斑块组,评估FAI_(PVAT)、VPCI与CHD的相关性.结果 112例患者中,CHD组71例,对照组41例;2组性别、年龄、FAI_(PVAT)及VPCI差异均有统计学意义.FAI_(PVAT)、VPCI与CHD呈正相关(r=0.445,P<0.01;r=0.669,P<0.01).对FAI_(PVAT)和VPCI作受试者工作特征(ROC)曲线分析,FAI_(PVAT) 曲线下面积(AUC)0.770,临界值-81.659 HU,敏感度 0.592,特异度 0.878;VPCI AUC 0.892,临界值 8.056,敏感度 0.887,特异度0.805.非钙化斑块组与钙化性斑块组FAI_(PVAT)、VPCI差异均有统计学意义;混合斑块组与钙化性斑块组FAI_(PVAT)、VPCI差异均有统计学意义.结论 FAI_(PVAT)、VPCI与CHD均有一定的相关性,FAI_(PVAT)、VPCI均能较准确地评估CHD及冠状动脉炎症水平,并且个体化的VPCI评估价值更高.Objective To explore the correlation between coronary fat attenuation index of perivascular adipose tissue(FAI_(PVAT)),as well as volumetric perivascular characterization index(VPCI),and coronary heart disease(CHD).Methods A total of 112 patients who underwent coronary computed tomography angiography(CCTA)and coronary angiography(CAG)examinations within 2 weeks were selected.The patients were divided into CHD group and control group according to the degree of coronary artery stenosis,and were divided into calcified plaque group,non-calcified plaque group and mixed plaque group according to the nature of plaque.The correlation between FAI_(PVAT),VPCI and CHD were evaluated.Results Of the 112 patients,71 patients in the CHD group and 41 patients in the control group.There were significant differences in gender,age,FAI_(PVAT) and VPCI between the two groups.FAI_(PVAT) and VPCI were positively correlated with CHD(r=0.445,P<0.01;r=0.669,P<0.01).FAI_(PVAT) and VPCI were analyzed by receiver operating characteristic(ROC)curve,the area under the curve(AUC)of FAI_(PVAT) was 0.770,the cut-off value was-81.659 HU,the sensitiv-ity was 0.592,and the specificity was 0.878,while the AUC of VPCI was 0.892,the cut-off value was 8.056,the sensitivity was 0.887,and the specificity was O.805.There were significant differences in FAI_(PVAT) and VPCI between non-calcified plaque group and calci-fied plaque group.FAI_(PVAT) and VPCI of mixed plaque group and caleified plaque group were significantly different.Conclusion FAI_(PVAT) and VPCI have some certain correlation with CHD.FAI_(PVAT) and VPCI can accurately evaluate the risk level of CHD and coronary artery inflammation,and the value of individualized VPCI is higher.

关 键 词：冠心病 冠状动脉造影 脂肪衰减指数 计算机体层成像 

分 类 号：R541.4[医药卫生—心血管疾病] R814.43[医药卫生—内科学] R814.42[医药卫生—临床医学]