原发不孕症患者对不同碘油对比剂在子宫输卵管造影后结果的比较分析  

Comparison analysis of the results of hysterosalpingography with different iodized oil-based contrast medium in primary infertility patients

作　　者：王银 杜子伟 徐文健[1] 李澄 李茂全[3] WANG Yin;DU Ziwei;XU Wenjian;LI Cheng;LI Maoquan(Department of Interventional,Women's Hospital of Nanjing Medical University,Nanjing Women and Children's Healthcare Hospital,Nanjing 210004,China;Department of Radiology,BenQ Hospital Affiliated to Nanjing Medical University,Nanjing 210001,China;Department of Interventional Vascular Surgery,the Tenth People's Hospital Affiliated to Tongji University,Shanghai 200072,China)

机构地区：[1]南京医科大学附属妇产医院(南京市妇幼保健院)介入科,江苏南京210004 [2]南京医科大学附属明基医院放射科,江苏南京210001 [3]同济大学附属第十人民医院介入血管外科,上海200072

出　　处：《实用放射学杂志》2024年第9期1514-1517,共4页Journal of Practical Radiology

摘　　要：目的 探讨原发不孕症患者对超液化罂粟乙碘油或普通碘化油进行子宫输卵管造影(HSG)相关结果的比较分析.方法 纳入212例原发不孕症且接受HSG检查患者,超液化罂粟乙碘油组96例,普通碘化油组116例.分析2组患者在HSG的疼痛视觉模拟量表(VAS)评分,不良反应(对比剂过敏反应、逆流等),24 h盆腔弥散情况以及HSG术后1年内自然妊娠情况.结果 超液化罂粟乙碘油组的VAS评分[(1.62±0.92)分]和对比剂逆流发生率(5.2%)低于普通碘化油组[(3.2±1.42)分和13.8%],2组差异有统计学意义(P<0.05).在24 h盆腔弥散情况中,超液化罂粟乙碘油组患者诊断盆腔轻度粘连率(26%)低于普通碘化油组(39.7%),差异有统计学意义(P=0.041).2组患者的1年内的自然妊娠率均有明显提升,但差异无明显统计学意义(P>0.05).结论 超液化罂粟乙碘油在原发不孕症患者HSG中疼痛轻,不良反应发生率低,盆腔弥散佳,并可提升自然妊娠率,是一种值得优先考虑的HSG对比剂.Objective To compare and analyze the results of hysterosalpingography(HSG)in primary infertility patients who received ultra-liquefied ethiodized poppyseed oil-based contrast medium or iodized oil-based contrast medium.Methods A total of 212 patients with primary infertility who received HSG examination were enrolled,of which 96 patients were in the ultra-liquefied ethiodized pop-pyseed oil-based contrast medium group,while l16 patients were in the iodized oil-based contrast medium group.The visual analogue scale(VAS)score of pain during HSG,adverse reactions(allergic reaction of contrast medium,contrast medium reflux,etc.),24 h-peri-toneal distribution and natural pregnancy rate within 1 year after HSG were analyzed between the two groups.Results The VAS scoreL(1.62±0.92)pointsJand the incidence of contrast medium reflux(5.2%)in the ultra-liquefied ethiodized poppyseed oil-based con-trast medium group were lower than those in the iodized oil-based contrast medium group[(3.2±1.42)points and 13.8%],respectively and the differences between the two groups were statistically significant(P<0.05).In the 24 h-peritoneal distribution,the diagnosis rate of mild pelvic adhesion in the ultra-liquefied ethiodized poppyseed oil-based contrast medium group(26%)was lower than that in the iodized oil-based contrast medium group(39.7%),and the difference was statistically significant(P=0.041).The natural pregnancy rate of the two groups within l year was significantly improved,but there was no significant difference between the two groups(P>0.05).Conclusion Ultra-liquefied ethiodized poppyseed oil-based contrast medium has less pain,lower incidence adverse reactions and better peritoneal distribution,and improve the natural pregnancy rate in primary infertility patients undergoing HSG.It is a high priority contrastmedium for HSG.

关 键 词：超液化罂粟乙碘油 碘化油 子宫输卵管造影 原发不孕症 自然妊娠率 

分 类 号：R711.6[医药卫生—妇产科学] R815[医药卫生—临床医学]