中国男男性行为者HIV暴露前预防用药知信行及影响因素的Meta分析  

Knowledge,attitudes,and practices regarding pre-exposure prophylaxis and its influencing factors among men who have sex with men in China:a meta-analysis

作　　者：雷达 靳廷丽[1] 刘家虹[1] LEI Da;JIN Tingli;LIU Jiahong(Jiangxi Provincial Center for Disease Control and Prevention,Jiangxi Prorincial Key laboratory of Major Epidemics Prevention and Control,Nanchang 330001,Jiangxi,China)

机构地区：[1]江西省疾病预防控制中心,重大疫情防控江西省重点实验室,南昌330001

出　　处：《中国艾滋病性病》2024年第9期999-1004,共6页Chinese Journal of Aids & STD

摘　　要：目的了解中国MSM对于HIV PrEP的认知、意愿、行为及相关影响因素。方法计算机检索Web of Science、PubMed、Science Direct、The Cochrane Library和万方、维普、中国知网、中国生物医学文献数据库中有关MSM对PrEP知识知晓、接受意愿、使用情况的横断面研究,运用RevMan 5.3软件进行Meta分析。结果共纳入33篇文献,样本总量为38577例MSM。Meta分析得出MSM对PrEP的知晓率为55%(95%CI:45%~65%),了解PrEP知识后对PrEP的接受意愿率为58%(95%CI:46%~71%),PrEP实际使用率为8%(95%CI:6%~11%)。文化程度为大专及以上(OR=1.95,95%CI:1.59~2.38)、月收入≥5000元(OR=1.62,95%CI:1.28~2.05)、性向为同性恋者(OR=2.01,95%CI:1.65~2.44)、自我感知HIV感染高风险(OR=2.12,95%CI:1.34~3.35)及知晓PrEP(OR=2.52,95%CI:1.71~3.72)是中国MSM使用PrEP的促进因素。结论我国MSM对于PrEP的认知及意愿水平一般,实际使用率更低。影响MSM使用PrEP的因素较多,根据不同影响因素探索符合我国MSM特点的PrEP服务模式,加强MSM对PrEP的意愿-行为转换,可有效促进PrEP的应用和推广。Objective To comprehend the level of awareness,willingness,and behaviors related to HIV preexposure prophylaxis(PrEP)among men who have sex with men(MSM)in China,as well as the factors influencing these variables.Methods A comprehensive search was conducted using databases such as Web of Science,PubMed,Science Direct,The Cochrane Library,Wanfang Data Knowledge Service Platform,VIP Chinese Journal Service Platform,China National Knowledge Infrastructure(CNKI),and the Chinese Biomedical Literature Database to identify cross-sectional studies on MSM's awareness,acceptance,and usage of PrEP.Meta-analysis was performed using RevMan 5.3 software.Results Thirty-three articles were included,representing a total sample of 38577 MSM.The meta-analysis showed that the rate of awareness of PrEP among MSM was 55%(95%CI:45%-65%),the willingness to accept PrEP after gaining knowledge of it was 58%(95%CI:46%-71%),and the actual usage rate of PrEP was 8%(95%CI:6%-11%).Factors that promoted PrEP use among Chinese MSM included having a college degree or higher(OR=1.95,95%CI:1.59-2.38),a monthly income of≥5000 yuan(OR=1.62,95%CI:1.28-2.05),identifying as homosexual(OR=2.01,95%CI:1.65-2.44),perceiving oneself at high risk of HIV infection(OR=2.12,95%CI:1.34-3.35),and being aware of PrEP(OR=2.52,95%CI:1.71-3.72).Conclusions Awareness and willingness to use PrEP among MSM in China are moderate,with even lower actual usage rates.A variety of factors influence PrEP use among MSM.By exploring PrEP service models that align with the characteristics of MSM in China and reinforcing the conversion of willingness to behavior,the application and promotion of PrEP can be effectively enhanced.

关 键 词：艾滋病病毒 暴露前预防 男男性行为者 认知、意愿、使用 

分 类 号：R373.9[医药卫生—病原生物学]