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作 者:薛亚斌 沈冬冬 彭佳炫 王炜东 张哲 XUE Yabin;SHEN Dongdong;PENG Jiaxuan;WANG Weidong;ZHANG Zhe(3^(rd) Cardiovascular Surgery of Jiaozuo Second People’s Hospital,Jiaozuo 450000 Henan,China)
机构地区:[1]焦作市第二人民医院血管外科普外三,河南焦作450000
出 处:《中国民康医学》2024年第20期19-21,25,共4页Medical Journal of Chinese People’s Health
摘 要:目的:观察腔内射频消融术治疗大隐静脉曲张患者的效果。方法:选取2020年6月至2023年10月该院收治的136例大隐静脉曲张患者进行前瞻性研究,按照随机数字表法将其分为对照组和研究组各68例。对照组实施大隐静脉高位结扎配合剥脱术治疗,研究组实施腔内射频消融术治疗,比较两组临床疗效,围术期指标(术中出血量、术后皮下淤血面积、首次下床活动时间、手术时间和住院时间)水平,手术前后氧化应激指标[肾上腺素(E)、皮质醇(Cor)]水平,并发症发生率,以及复发率。结果:研究组治疗总有效率为93.48%(65/68),高于对照组的77.78%(58/68),差异有统计学意义(P<0.05);研究组术中出血量、术后皮下淤血面积均少于对照组,首次下床活动时间、手术时间和住院时间均短于对照组,差异有统计学意义(P<0.05);术后3 d,两组E、Cor水平均高于术前,但研究组低于对照组,差异有统计学意义(P<0.05);研究组并发症发生率、复发率均低于对照组,差异有统计学意义(P<0.05)。结论:腔内射频消融术治疗大隐静脉曲张患者,可提高临床疗效,改善围手术期指标水平,减轻机体氧化应激反应,降低并发症发生率和复发率,效果优于高位结扎配合剥脱术。Objective:To observe effects of endovenous radiofrequency ablation in treatment of patients with varicose great saphenous veins.Methods:A prospective study was conducted on 136 patients with varicose great saphenous veins admitted to the hospital from June 2020 to October 2023.According to the random number table method,they were divided into control group and study group,68 cases in each group.The control group was treated with high ligation of great saphenous vein combined with stripping,while the study group was treated with endovenous radiofrequency ablation.The clinical efficacy,the perioperative indexes(intraoperative blood loss,postoperative subcutaneous congestion area,first out-of-bed time,operation time and hospitalization time),the oxidative stress indexes[epinephrine(E),cortisol(Cor)]levels before and after the surgery,the incidence of complications,and the recurrence rate were compared between the two groups.Results:The total effective rate of the study group was 93.48%(65/68),which was higher than that of the control group 77.78%(58/68),and the difference was statistically significant(P<0.05).The intraoperative blood loss and the postoperative subcutaneous congestion area in the study group were less than those in the control group;the first out-of-bed time,the operation time and the hospitalization time were shorter than those in the control group;and the differences were statistically significant(P<0.05).3 days after the surgery,the levels of E and Cor in the two groups were higher than those before the surgery,but those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Further,the incidence of complications and recurrence rate in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Conclusions:Endovenous radiofrequency ablation in the treatment of the patients with varicose great saphenous veins can improve the clinical efficacy,improve the levels of perioperativ
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