经阴道三维彩色多普勒超声评估子宫内膜容受性对不孕症患者IVF-ET妊娠结局的预测价值  

Predictive value of endometrial receptivity assessed by transvaginal three-dimensional color Doppler ultrasound for IVF-ET pregnancy outcome in infertile patients

作　　者：徐玲 XU Ling(Reproductive Medicine Center of Joint Logistics Support Force 988th Hospital,Jiaozuo 454150 Henan,China)

机构地区：[1]联勤保障部队第九八八医院生殖医学中心,河南焦作454150

出　　处：《中国民康医学》2024年第20期117-119,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:分析经阴道三维彩色多普勒超声(3D-TVUS)评估子宫内膜容受性(ER)对不孕症患者体外受精-胚胎移植(IVF-ET)妊娠结局的预测价值。方法:回顾性分析2022年10月至2023年10月该院收治的90例接受IVF-ET的不孕症患者的临床资料,按照妊娠结局不同将其分为妊娠组和未妊娠组,比较两组经阴道3D-TVUS检查ER参数[子宫内膜厚度、子宫内膜容积、血管化指数(VI)、血流指数(FI)、血管化血流指数(VFI)],采用受试者工作特征(ROC)曲线分析ER参数对不孕症患者IVF-ET妊娠失败的预测价值。结果:两组子宫内膜厚度比较,差异无统计学意义(P>0.05);妊娠组子宫内膜容积、VI、FI、VFI均高于未妊娠组,差异有统计学意义(P<0.05);ROC曲线分析结果显示,子宫内膜容积、VI、FI、VFI单项及联合检测预测不孕症患者IVF-ET妊娠失败的曲线下面积分别为0.779、0.872、0.759、0.768、0.949,联合检测预测价值高于四者单项检测。结论:子宫内膜容积、VI、FI、VFI联合检测对不孕症患者IVF-ET妊娠失败的预测价值高于四者单项检测。Objective:To analyze predictive value of endometrial receptivity(ER)assessed by transvaginal three-dimensional color Doppler ultrasound(3D-TVUS)for pregnancy outcome of in vitro fertilization-embryo transfer(IVF-ET)in infertile patients.Methods:The clinical data of 90 infertility patients who received IVF-ET in this hospital from October 2022 to October 2023 were retrospectively analyzed.According to the different pregnancy outcomes,they were divided into pregnancy group and non-pregnancy group.The ER parameters[endometrial thickness,endometrial volume,vascularization index(VI),blood flow index(FI),vascularization blood flow index(VFI)]assessed by transvaginal 3D-TVUS were compared between the two groups.The receiver operating characteristic(ROC)curve was used to analyze the predictive value of ER parameters for IVF-ET pregnancy failure in the infertile patients.Results:There was no significant difference in the endometrial thickness between the two groups(P>0.05).The levels of endometrial volume,VI,FI and VFI in the pregnancy group were higher than those in the non-pregnancy group,and the differences were statistically significant(P<0.05).The ROC curve analysis showed that the area under the curve of single and combined detection of endometrial volume,VI,FI,VFI in the prediction of IVF-ET pregnancy failure in the infertile patients was 0.779,0.872,0.759,0.768 and 0.949,respectively.The predictive value of combined detection was higher than that of single detection.Conclusions:The predictive value of combined detection of endometrial volume,VI,FI and VFI for IVF-ET pregnancy failure in the infertile patients is higher than that of single detection of the four.

关 键 词：不孕症 体外受精-胚胎移植 妊娠结局 经阴道三维彩色多普勒超声 子宫内膜容受性 检测 诊断 

分 类 号：R711[医药卫生—妇产科学]