间苯三酚注射液对产妇宫颈软化、产程进展和妊娠结局的影响  

The Effect of Phloroglucinol Injection on Maternal Cervical Softening,Labor Progression and Pregnancy Outcomes

作　　者：王芬珠 WANG Fen-zhu(Department of Gynaecology and Obstetrics,Anfu County People’s Hospital,Anfu 343200,China)

机构地区：[1]安福县人民医院妇产科,江西安福343200

出　　处：《实用临床医学（江西）》2024年第5期62-65,共4页Practical Clinical Medicine

基　　金：吉安市指导性科技计划项目(20233-043307)。

摘　　要：目的观察间苯三酚注射对产妇宫颈软化、产程进展的促进作用以及对妊娠结局的影响。方法选取2020—2022年收治的82例经阴道自然分娩的初产妇,按随机数字表法将其分为2组:对照组(n=41)产妇于第一产程潜伏期单纯应用缩宫素,观察组(n=41)在对照组的基础上,于产妇第一产程活跃期后肌内注射80 mg间苯三酚。比较2组宫颈软化优良率、中转剖宫率、产程时间、产后总出血量、新生儿Apgar评分及围生期不良事件发生情况。结果观察组产妇宫颈软化优良率为92.68%,高于对照组的75.61%;而中转剖宫率为2.44%低于对照组的21.95%(P<0.05)。观察组产妇第一产程潜伏期、活跃期及第二产程、第三产程时间短于对照组,且产后总出血量低于对照组(P<0.05)。观察组1 min新生儿Apgar评分高于对照组(P<0.05),而2组5、10 min新生儿Apgar评分比较差异无统计学意义(P>0.05)。2组产妇产后宫颈裂伤、宫颈感染、宫颈水肿等围生期不良事件总发生率比较差异无统计学意义(P>0.05)。结论缩宫素联合间苯三酚注射能够促进产妇宫颈软化,加快产程进展,减少产后出血量,优化妊娠分娩结局,改善新生儿预后。Objective To investigate promotional effect of phloroglucinol injection on cervical softening,labor progression,and pregnancy outcome in primiparas.Methods A total of 82 cases of primiparas with natural vaginal delivery hospitalized from 2020 to 2022 were selected and divided into 2 groups using the randomized numerical table method:the control group(n=41),which received oxytocin alone during the latent phase of the first stage of labor,and the observation group(n=41),which were further injected intramuscularly with 80 mg of phloroglucinol after the first active phase of the first stage of labor.The excellent rate of cervical softening,rate of intermediate cesarean section,duration of labor,total postpartum hemorrhage,neonatal Apgar score,and adverse events were compared between the 2 groups.Results The excellent rate of maternal cervical softening in the observation group was 92.68%,higher than that of 75.61%in the control group,while the rate of intermediate cesarean section was 2.44%,lower than that of 21.95%in the control group(P<0.05).The latent and active periods of the first stage of labor and the duration of the second and third stages of labor were shorter in the observation group than those in the control group,and the total postpartum hemorrhage was lower than that in the control group(P<0.05).The Apgar scores of newborns at 1 min after birth were higher in the observation group than those in the control group(P<0.05);the difference between the Apgar scores of newborns at 5 min and 10 min was not statistically significant in the 2 groups(P>0.05);the difference between the total incidences of perinatal adverse events in the postpartum period,such as cervical lacerations,cervical infections and cervical edema,was not statistically significant in the 2 groups(P>0.05).Conclusion Our findings suggest that by promoting cervical softening and reducing postpartum bleeding,phloroglucinol injection for primiparas combined with oxytocin can accelerate labor progress,optimize pregnancy and delivery outcome,and imp

关 键 词：初产妇 间苯三酚 宫颈软化 产程 妊娠结局 新生儿Apgar评分 

分 类 号：R714.3[医药卫生—妇产科学]