炙甘草汤治疗蒽环类药物相关性室性心律失常  

Zhigancao Decoction in the Treatment of Anthracyclines-associated Ventricular Arrhythmias

作　　者：邢晶晶 李鸿真 庄欣[3] 杨洁[3] XING Jingjing;LI Hongzhen;ZHUANG Xin;YANG Jie(The First Clinical Medical College,Shandong University of Traditional Chinese Medicine,Shandong Province,Jinan 250014,China;Department of Anesthesiology,Shandong Province Second People’s Hospital,Shandong Province,Jinan 250014,China;Department of Cardiology,Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Shandong Province,Jinan 250014,China)

机构地区：[1]山东中医药大学第一临床医学院,山东济南250014 [2]山东省第二人民医院麻醉科,山东济南250014 [3]山东中医药大学附属医院心内科,山东济南250014

出　　处：《中国中医药现代远程教育》2024年第22期87-90,共4页Chinese Medicine Modern Distance Education of China

基　　金：国家自然科学基金青年科学基金项目【No.81804061】;山东省中医药科技发展计划项目【No.2019-0099】。

摘　　要：蒽环类药物(Anthracyclines,ANT)相关性室性心律失常是肿瘤患者因使用ANT进行抗肿瘤治疗而产生的剂量性心脏毒性引起的不良反应,但目前对于使用ANT所引起的室性心律失常暂无有效的预防及治疗措施,故成为如今肿瘤心脏学科领域关注的重点。传统中医药文化历史悠久,有着丰富的理论和经验。目前,临床上采用中西医结合治疗肿瘤的方法,对于减轻ANT所导致的心脏毒性取得了较好的效果。中医药干预ANT所致的心脏毒性具有较为重要的临床意义。此病根据临床症状归为中医学“心悸”范畴,运用经典名方炙甘草汤治疗,可减少或缓解肿瘤患者使用ANT化疗后出现的药物相关性室性心律失常,改善临床症状。Anthracyclines(ANT)-associated ventricular arrhythmias are adverse reactions caused by dose cardiotoxicity caused by ANT in tumor patients.However,there is currently no effective treatment or preventive measure for ventricular arrhythmias caused by ANT.Therefore,it has become the focus of attention in the field of oncology and cardiology.Traditional Chinese medicine culture has a long history,rich theory and experience summary.At present,the combination of traditional Chinese and western medicine in the clinical treatment of tumor patients has achieved a good effect in alleviating the cardiotoxicity caused by ANT.The intervention of tra-ditional Chinese medicine in cardiotoxicity caused by ANT has important clinical significance.According to the clinical symptoms of this disease classified into the category of“palpitation”of traditional Chinese medicine,the treatment with the classic prescription Zhi-gancao decoction can reduce or relieve drug-related ventricular arrhythmias in tumor patients after ANT chemotherapy,and improve the clinical symptoms.

关 键 词：心悸 室性心律失常 蒽环类药物 炙甘草汤 中医药疗法 

分 类 号：R259[医药卫生—中西医结合]