改良取材涂片法真菌镜检对股癣复发率的应用价值  

Application Value of Modified Sampling Smear Method with Fungal Microscopy on Recurrence Rate of Tinea Cruris

作　　者：许立明 胡莉 吴桂珍 吴海宝 胡伟威 XU Liming;HU Li;WU Guizhen;WU Haibao;HU Weiwei(Department of Emergency Medicine,Xinyu Yinhe Hospital,Xinyu 338000,Jiangxi,China;Department of Laboratory Medicine,Xinyu Yinhe Hospital,Xinyu 338000,Jiangxi,China;Department of Diabetes Medicine,Xinyu Yinhe Hospital,Xinyu 338000,Jiangxi,China;Department of Dermatology,Xinyu Yinhe Hospital,Xinyu 338000,Jiangxi,China)

机构地区：[1]新余银河医院急诊内科,江西新余338000 [2]新余银河医院检验科,江西新余338000 [3]新余银河医院糖尿病内科,江西新余338000 [4]新余银河医院皮肤科,江西新余338000

出　　处：《医学信息》2024年第20期151-154,共4页Journal of Medical Information

基　　金：新余市科学技术局项目(编号:20213090959)。

摘　　要：目的研究改良取材涂片法真菌镜检对股癣复发率的应用价值。方法选取2020年10月-2022年9月我院收治的100例股癣患者为研究对象,采用随机数字表法分为对照组和观察组,各组50例。两组患者均采用伊曲康唑胶囊联合硝酸咪康唑乳膏治疗,连续治疗2周后,观察组采用改良取材涂片镜检,对镜检真菌(+)的患者仍然继续治疗2周,而对照组通过临床症状及外观“判愈”对症状改善不明显的患者仍然继续治疗2周,比较两组真菌完全清除率、临床症状评分、股癣复发率、治疗费用以及复发恐惧评分。结果观察组真菌完全清除率为98.00%,高于对照组的86.00%(P<0.05);观察组治疗后皮肤损伤面积、疼痛、瘙痒、水疱、红斑、角化评分均低于对照组(P<0.05);停药1个月后随访,观察组复发率为2.00%,低于对照组的12.00%(P<0.05);观察组治疗总费用低于对照组(P<0.05);观察组FCR中严重程度、触发因素、心理痛苦、严重程度、应对策略、功能障碍、洞察力、寻求安慰评分均低于对照组(P<0.05)。结论改良取材涂片法真菌镜检在股癣治疗中具有重要价值,可提高真菌完全清除率,减轻患者临床症状,降低股癣复发率,减少患者治疗费用,值得临床加以应用。Objective To study the application value of modified sampling smear method with fungal microscopy in the recurrence rate of tinea cruris.Methods A total of 100 patients with tinea cruris admitted to the our hospital from October 2020 to September 2022 were selected as the research objects.They were divided into control group and observation group by random number table method,with 50 patients in each group.Both groups were treated with itraconazole capsules combined with miconazole nitrate cream.After 2 weeks of continuous treatment,the observation group was treated with modified sampling smear method with fungal microscopy,the patients with microscopic examination of fungi(+)were still treated for 2 weeks,while the control group was treated with clinical symptoms and appearance judgment,the patients with no obvious improvement of symptoms were still treated for 2 weeks.The complete fungal clearance rate,clinical symptom score,recurrence rate of tinea cruris,treatment cost and recurrence fear score were compared between the two groups.Results The complete clearance rate of fungi in the observation group was 98.00%,which was higher than 86.00%in the control group(P<0.05).After treatment,the scores of skin injury area,pain,itching,blisters,erythema and keratosis in the observation group were lower than those in the control group(P<0.05).One month after drug withdrawal,the recurrence rate of the observation group was 2.00%,which was lower than 12.00%of the control group(P<0.05).The total cost of treatment in the observation group was lower than that in the control group(P<0.05).The scores of severity,trigger factors,psychological pain,severity,coping strategies,dysfunction,insight and seeking comfort in FCR in the observation group were lower than those in the control group(P<0.05).Conclusion The modified sampling smear method with fungal microscopy has important value in the treatment of tinea cruris.It can improve the complete clearance rate of fungi,reduce the clinical symptoms of patients,reduce the recurrence r

关 键 词：改良取材涂片法 真菌镜检 股癣复发率 

分 类 号：R446.5[医药卫生—诊断学]