妊娠糖尿病患者检测血浆D-二聚体与纤维蛋白原的临床价值  

Clinical Value of Plasma D-Dimer and Fibrinogen in Pregnant Women with Diabetes

作　　者：温春凤 温丽钦 邱华 WEN Chunfeng;WEN Liqin;QIU Hua(Department of Laboratory,Fuqing Maternal and Child Health Hospital,Fuqing 350300,China)

机构地区：[1]福建省福清市妇幼保健院检验科,福清350300

出　　处：《中国医药指南》2024年第30期105-107,共3页Guide of China Medicine

摘　　要：目的 探讨分析妊娠糖尿病患者检测血浆D-二聚体与纤维蛋白原的临床价值。方法 选取2022年1月至2023年2月我院治疗的妊娠糖尿病患者施以研究,纳入患者86例,作为观察组,同时纳入同时段健康孕妇86例,作为对照组,对参与本研究所有受检者,均施以血浆D-二聚体与纤维蛋白原的检测工作,对最终研究结果比较分析。结果 产前1 d与产前24~30周观察组的D-二聚体与纤维蛋白原水平均高于对照组(P <0.05)。对照组顺产概率更高,观察组出现不良孕妇结局、不良新生儿结局概率更高(P <0.05)。结论 对于存在妊娠期糖尿病患者,其血浆D-二聚体与纤维蛋白原水平要明显高于正常健康孕产妇,参考这些指标有助于更好判断患者目前是否呈现高凝状态病变,对糖尿病病情发展的判断也更准确。Objective To study the analysis of the detection of plasma D-dimer gestational diabetes patients and the clinical value of fibrinogen.Methods A total of 86 patients with gestational diabetes mellitus treated in our hospital from January 2022 to February 2023 were included as the observation group,and 86 healthy pregnant women at the same time were included as the control group.All participants in this study were subjected to plasma D-dimer and fibrinogen detection,and the final research results were compared and analyzed.Results The levels of D-D and FIB in the observation group at 1 day and 24-30 weeks before delivery were higher than those in the control group(P<0.05).The control group had a higher probability of vaginal delivery,while the observation group had a higher probability of adverse maternal and neonatal outcomes(P<0.05).Conclusions For patients with gestational diabetes mellitus,the plasma D-dimer and fibrinogen levels are significantly higher than those of normal healthy pregnant women,which is better to judge whether the patients present with hypercoagulable state lesions and more accurate to judge the development of diabetes.

关 键 词：妊娠糖尿病 血浆D-二聚体 纤维蛋白原 

分 类 号：R714.256[医药卫生—妇产科学]