Death from Fat Embolism after Lipectomy in a Patient with Madelung’s Disease  

作　　者：Xing-An Yang Teng-Fei Yang Fu Zhang Jiang-Wei Kong Zi-Lin Meng Xin-Biao Liao Pei-Yu Liang Dong-Ri Li 

机构地区：[1]Department of Forensic Pathology,School of Forensic Medicine,Southern Medical University,Guangzhou,Guangdong,China [2]Guangdong Public Security Department,Forensic Pathology Lab,Guangzhou,Guangdong,China

出　　处：《Journal of Forensic Science and Medicine》2024年第2期148-151,共4页法庭科学与法医学杂志（英文）

基　　金：supported by the(National Natural Science Fund#1)under Grant(number 81971802);(National College Students Innovation and Entrepreneurship Training Program#2)under Grant(202112121023).

摘　　要：A 56-year-old man with a long history of alcoholism and a palpable raised mass about 23 cm×12 cm in size on his neck was diagnosed with Madelung’s disease(MD);the patient also had hyperuricemia.On day 1,he underwent neck lipoma tissue resection and suddenly had dyspnea 9 h after the operation,which was followed by cardiac arrest.After heart rate resuscitation,he developed a heartbeat,but he remained in a coma and died 9 days after the operation.No obvious pathological tracheal compression from a hematoma was observed while evaluating the patient’s neck on autopsy.On microscopy,the patient had an extensive pulmonary fat embolism,partial alveolar septal rupture and hemorrhage,and fat particles,and there was extensive infiltration of macrophages,which had phagocytosed fat particles,in the alveolar cavity.There was also evidence of pulmonary infection and hypoxic-ischemic encephalopathy.The cause of death was postoperative pulmonary fat embolism resulting in pneumonia and central nervous system injury.This is the first report of a patient with MD who died of a fatal pulmonary fat embolism after neck lipoma tissue resection.Medicolegal experts and clinicians should pay sufficient attention to this case.

关 键 词：Forensic pathology madelung’s disease pulmonary fat embolism 

分 类 号：R653[医药卫生—外科学]