Emulation of Brain Metabolic Activities Based on a Dynamically Controllable Optical Phantom  

作　　者：Yuxiang Lin Cheng Chen Zhouchen Ma Nabil Sabor Yanyan Wei Tianhong Zhang Mohamad Sawan Guoxing Wang Jian Zhao 

机构地区：[1]Department of Micro-Nano Electronics,Shanghai Jiao Tong University,Shanghai,China [2]Electrical Engineering Department,Faculty of Engineering,Assiut University,Assiut,Egypt [3]Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Shanghai,China [4]CenBRAIN Neurotech,School of Engineering,Westlake University,Hangzhou,China

出　　处：《Cyborg and Bionic Systems》2023年第1期84-92,共9页类生命系统（英文）

基　　金：supported by the National Key Research and Development Program of China under Grant No.STI2030-Major Projects 2022ZD0208500.

摘　　要：This paper presents a dynamic optical phantom for the simulation of metabolic activities in the brain,and a linear equivalent model is built for control voltage versus substance concentration.A solid-solid dynamic optical phantom is realized by using liquid crystal film as a voltage-controlled light intensity regulator on the surface of basic phantom,which uses epoxy resin as matrix material and nanometer carbon powder and titanium dioxide powder as absorption and scattering dopants,respectively.The dynamic phantom could mimic near-infrared spectrum(NIRS)signals with sampling rate up to 10 Hz,and the maximum simulation errors for oxy-hemoglobin and deoxy-hemoglobin concentrations varying in the range of 1μmol/l are 7.0%and 17.9%,respectively.Compared with similar solid biomimetic phantoms,the adjustable mimic substance concentration range is extended by an order of magnitude,which meets the simulation requirements of most brain NIRS signals.

关 键 词：dynamic POWDER TITANIUM 

分 类 号：O43[机械工程—光学工程]