PVA/CS与PEO/SA双层纳米纤维膜的制备及其性能  

Preparation of PVA/CS and PEO/SA bilayer nanofiber films and their properties

作　　者：邓丽珊 侯超 余景红 郑心怡 雷静秋 李庭晓 辛斌杰[1] DENG Lishan;HOU Chao;YU Jinghong;ZHENG Xinyi;LEI Jingqiu;LI Tingxiao;XIN Binjie(School of Textile and Fashion,Shanghai University of Engineering Science,Shanghai 201620,China;College of Textiles,Donghua University,Shanghai 201620,China)

机构地区：[1]上海工程技术大学纺织服装学院,上海201620 [2]东华大学纺织学院,上海201620

出　　处：《上海纺织科技》2024年第10期20-24,共5页Shanghai Textile Science & Technology

摘　　要：为研究具有高生物相容性的原料在医用敷料方面的应用,利用静电纺丝法制备了PVA/CS和PEO/SA双层纳米纤维膜,并进行拒水整理和交联处理,分析双层纳米纤维膜的机械性能和抗菌性能。加入盐酸左氧氟沙星并研究其药物缓释机理。研究表明:PVA质量分数为14%、CS质量分数为3%的纺丝液在纺丝电压26 kV、接收距离20 cm时具有较好的可纺性;PEO质量分数为10%、SA质量分数为2%的纺丝液在纺丝电压27 kV、接收距离20 cm时具有较好的可纺性。制备的PVA/CS混纺和PEO/SA混纺的双层纳米纤维膜具有亲水性和潜在的抗菌性,在生物医疗领域具有独特的优势。To investigate the application of highly biocompatible raw materials in medical dressings,PVA/CS and PEO/SA bilayer nanofiber membranes are prepared using electrospinning method,and subjected to water repellent treatment and cross-linking treatment.The mechanical and antibacterial properties of the bilayer nanofiber membranes are analyzed.Levofloxacin hydrochloride is added and its sustained-release mechanism is studied.The results show that the spinning solution with PVA mass fraction of 14%and CS mass fraction of 3%has good spinnability at spinning voltage of 26 kV and receiving distance of 20 cm,while the spinning solution with PEO mass fraction of 10%and SA mass fraction of 2%has good spinnability at spinning voltage of 27 kV and receiving distance of 20 cm.The prepared bilayer nanofiber membranes of PVA/CS blend and PEO/SA blend have hydrophilicity and potential antibacterial properties,which have unique advantages in the field of biomedicine.

关 键 词：聚乙烯醇 壳聚糖 聚氧化乙烯 海藻酸钠 静电纺丝 

分 类 号：TS176.4[轻工技术与工程—纺织材料与纺织品设计]