河北省2018—2023年人间布鲁菌病流行特征及空间聚集性分析  

Epidemiological characteristics and spatial-temporal distribution of human brucellosis in Hebei Province,2018-2023

作　　者：曹玉雯[1] 姜霞[1] 钱振宇[1] 张海霞[1] 贾肇一[1] 刘晓丽[1] CAO Yuwen;JIANG Xia;QIAN Zhenyu;ZHANG Haixia;JIA Zhaoyi;LIU Xiaoli(Hebei Provincial Key Laboratory of Pathogens and Epidemiology of Infection Diseases,Hebei Provincial Center for Disease Control and Prevention,Shijiazhuang,Hebei 050021,China)

机构地区：[1]河北省疾病预防控制中心,河北省传染病病原鉴定分析与流行病学重点实验室,河北石家庄050021

出　　处：《中国热带医学》2024年第9期1047-1051,共5页China Tropical Medicine

基　　金：河北省医学科学研究课题计划项目(No.20231183)。

摘　　要：目的了解河北省人间布鲁菌病(简称布病)流行病学特征,探讨其防治策略与措施。方法收集“传染病报告信息管理系统”中河北省报告的布病个案数据,描述总体疫情概况,对布病流行病学特征进行分析,应用空间自相关分析方法,对县级布病发病率情况进行分析,探索布病空间分布特征。结果2018—2023年河北省共报告布病新发病例21718例,死亡病例1例(2021年)。年发病率为3.91/10万~6.26/10万,年均报告发病率为4.84/10万。布病发病高峰期在4—7月,有明显的季节性特征。男性发病高于女性,男女性别比为2.81∶1。发病年龄集中在30~<70岁,占总发病数的85.33%。发病人群主要职业为农民,占88.59%。年均发病率前3位的地市是张家口市、承德市和衡水市,共报告7801例,占全省总发病数的35.92%。全局空间自相关分析结果显示,2018—2023年间河北省布病发病均呈聚集性分布,局部空间自相关分析结果存在热点地区,6年间河北省布病高发区主要集中在河北省北部的张家口市(13.6513/10万)和承德市(13.1167/10万);“低-低”聚集区主要分布在唐山市、石家庄市和邯郸市;低-高聚集区主要围绕在高高聚集区周边,位于张家口、承德市部分县(区)。结论河北省人间布鲁菌病防控形势依然严峻,建议加强传染源的管理,加大布鲁菌病监测力度,重点开展对高危人群的宣传教育和行为干预,针对热点地区加大防控力度。Objective To analyze the epidemiological characteristics of human brucellosis in Hebei Province,and to explore strategies and measures for its prevention and control.Methods Data on brucellosis cases reported in Hebei Province were collected from the National Notifiable Infectious Disease Reporting Information System.The total situation of brucellosis was described,and the epidemiological characteristics of brucellosis in Hebei Province were analyzed.The spatial autocorrelation analysis method was used to explore the spatial distribution characteristics of brucellosis incidence at the county level in Hebei Province.Results From 2018 to 2023,a total of 21718 cases of brucellosis were reported in Hebei Province,with 1 death(in 2021).The annual incidence rate fluctuated between 3.91/100000 to 6.26/100000,with an average annual reported incidence rate of 4.84/100000.The epidemic peak was from April to July,showing obvious seasonal characteristics.The incidence in males was higher than in females,with a male-to-female ratio of 2.81∶1.The incidence age was concentrated 30-<70 years,accounting for 85.33%of the total cases.The primary occupational group affected was farmers,accounting for 88.59%.The top three cities with the highest average annual incidence rate were Zhangjiakou,Chengde,and Hengshui,which reported a total of 7801 cases,representing 35.92%of the total cases in the province.From the perspective of spatial distribution:the global spatial autocorrelation analysis showed clustering distribution in Hebei Province from 2018 to 2023,and there were hot spots in local spatial autocorrelation analysis.The high-incidence areas of brucellosis were mainly concentrated in Zhangjiakou(13.6513/100000)and Chengde(13.1167/100000)in the north of Hebei Province during the past six years.The"low-low"clustering areas were mainly distributed in Tangshan,Shijiazhuang,and Handan.The"low-high"clustering areas were mainly located around the"high-high"cluster areas,in some counties of Zhangjiakou and Chengde.Conclusions The situat

关 键 词：布鲁菌病 流行病学特征 空间自相关 河北省 

分 类 号：R516[医药卫生—内科学]