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作 者:韦春冕 赵艳丽 李丹丹 谢准 张保得 余红娅 邱勇 徐福荣 WEI Chunmian;ZHAO Yanli;LI Dandan;XIE Zhun;ZHANG Baode;YU Hongya;QIU Yong;XUFurong(Yunnan University of Chinese Medicine,Yunnan Key Laboratory of Southern Medicine Sustainable Utilization,Kunming 650500,China;Yunnan Key Laboratory of Dai and Yi Medicines,Kunming 650500,China)
机构地区:[1]云南中医药大学云南省南药可持续利用重点实验室,云南昆明650500 [2]云南省傣医药与彝医药重点实验室,云南昆明650500
出 处:《中草药》2024年第17期6026-6039,共14页Chinese Traditional and Herbal Drugs
基 金:云南省科技厅科技专项(202304BI090004);云南省科技人才和平台计划(202105AG070012XS23071)。
摘 要:三七Panax notoginseng是传统的活血化瘀药,疗效俱佳,应用广泛。但传统的三七品质评价方式存在一定局限性,而“辨状论质”是历代医药学家实践经验的成果与智慧结晶,在三七质量评价中具有重要的指导作用。通过查阅本草书籍和相关文献资料,对三七“辨状论质”理论的历史沿革、三七状-质相关性分析的现代研究及其品质成因进行综述,并对三七“辨状论质”的未来应用进行展望,建议后续应充分利用生物药效评价等技术,加强三七整体性状和化学成分的关联分析,建立三七“性状-成分-药效”相关联的新模式和“性状-质量标志物-生物效应”的模式,为建立科学的三七质量评价方法提供参考。Sanqi(Panax notoginseng)is a traditional blood-activating and blood stasis-removing drug with excellent curative effects and wide application.However,the traditional quality evaluation methods of Panax notoginseng have certain limitations.The“quality evaluation through morphological identification”is the achievement and wisdom crystal from the practical experience of ancient pharmaceutical scientists,which has an important guiding role in the quality evaluation of P.notoginseng.By consulting herbal books and relevant literature,this review mainly summarizes the historical evolution of the theory of“quality evaluation through morphological identification”of Panax notoginseng,modern research on the correlation analysis of the appearance and quality of P.notoginseng and the causes of quality formation,and the future application of“quality evaluation through morphological identification”of P.notoginseng has prospected.It is recommended that subsequent studies should make full use of biological efficacy evaluation,and other technologies,strengthen the correlation analysis of the overall characteristics and chemical components of P.notoginseng,establish a new model of“character-ingredient-pharmaceutical effect”correlation and a model of“character-quality marker-biological effect”of P.notoginseng,and provide a reference for establishing a scientific method of quality evaluation of P.notoginseng.
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