红参的炮制工艺及质量评价研究进展  

Research progress on processing technology and quality evaluation of Ginseng Radix et Rhizoma Rubra

作　　者：袁佳宝 曹帅 李丽敏 胡青 毛秀红 季申 YUAN Jiabao;CAO Shuai;LI Limin;HU Qing;MAO Xiuhong;JI Shen(School of Pharmacy,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;National Medical Products Administration Key Laboratory for Quality Control of Traditional Chinese Medicine,Shanghai Institute for Food and Drug Control,Shanghai 201203,China)

机构地区：[1]上海中医药大学中药学院,上海201203 [2]上海市食品药品检验研究院,国家药品监督管理局中药质量控制重点实验室,上海201203

出　　处：《中草药》2024年第18期6437-6447,共11页Chinese Traditional and Herbal Drugs

基　　金：上海市中药和保健食品品质与安全检测专业技术服务平台(21DZ2290200);国家药品监督管理局监管科学体系建设重点项目(RS2024Z006)。

摘　　要：红参Ginseng Radix et Rhizoma Rubra为五加科植物人参Panax ginseng的栽培品经蒸制后的干燥根和根茎,具有大补元气、复脉固脱、益气摄血的功效。文献报道红参的化学成分主要有皂苷类、糖类、挥发油类等,药理作用主要有增强免疫、抗肿瘤、抗氧化等。而红参炮制工艺参数对其质量和临床疗效影响较大,且历版《中国药典》及地方炮制规范尚未对红参的炮制工艺参数进行明确规定,从而导致市面上的红参药材的质量参差不齐,质量评价指标也无法区别于人参,体现红参的炮制意义。基于现阶段红参炮制工艺及质量评价研究进展及存在的问题提出思考与解决方向,以期为红参质量评价提供依据。Hongshen(Ginseng Radix et Rhizoma Rubra)is the dried root and rhizome of the cultivated ginseng plant Renshen(Panax ginseng)from the Araliaceae family,which has been steamed.It is known for its effects in greatly tonifying the original qi,strengthening the pulse to relieve desertion and benefiting qi for consolidating blood.It has been reported that the chemical components of Ginseng Radix et Rhizoma Rubra mainly include saponins,sugars,volatile oils,etc.The pharmacological effects are mainly to enhance immunity,antitumor,antioxidant and so on.However,the processing parameters of Ginseng Radix et Rhizoma Rubra have great influence on its quality and clinical efficacy.Various editions of the“Chinese Pharmacopoeia”and local processing standards have not yet provided clear specifications for the processing parameters of Ginseng Radix et Rhizoma Rubra.As a result,the quality of Ginseng Radix et Rhizoma Rubra medicinal materials on the market varies,and quality evaluation indicators cannot be distinguished from those of P.ginseng,which fails to reflect the significance of the processing of Ginseng Radix et Rhizoma Rubra.Therefore,based on the research progress current issues with the processing techniques and quality evaluation of Ginseng Radix et Rhizoma Rubra,this article proposes considerations and directions for resolution,in order to provide a theoretical basis for the quality evaluation of Ginseng Radix et Rhizoma Rubra.

关 键 词：红参 人参 炮制工艺 质量评价 原人参二醇型皂苷 

分 类 号：R284.1[医药卫生—中药学]