2型糖尿病女性性功能障碍相关危险因素分析  

Analysis of risk factors related to female sexual dysfunction in type 2 diabetic patients

作　　者：张净 吴立[1] 路丽[1] 靳丽 Zhang Jing;Wu Li;Lu Li;Jin Li(Department of Endocrinology,Taiyuan People′s Hospital,Taiyuan030001,China;Department ofPediatrics,the First Affiliated Hospital of Shanxi Medical University,Taiyuan 030001,China)

机构地区：[1]太原市人民医院内分泌科,太原030001 [2]山西医科大学第一医院儿科,太原030001

出　　处：《实用医技杂志》2024年第8期539-543,共5页Journal of Practical Medical Techniques

基　　金：太原市“六个一批”科研项目(Y2022003)。

摘　　要：目的探讨2型糖尿病女性性功能障碍(FSD)的特点,并分析其发生的相关危险因素。方法选择2022年9月至2023年12月我院内分泌科住院部门诊2型糖尿病女性患者252例,根据有无FSD,分为试验组1(单纯糖尿病组)120例、试验组2(糖尿病+FSD)132例。同期健康女性138名作为对照组,采用女性性功能指数评分表(FSFI)问卷评估各组性功能,logistic回归分析危险因素。结果2型糖尿病FSD的发病率52.4%(132/252)高于对照组25.4%(35/138)。与对照组比较,试验组1和试验组2雌激素(E2)降低,卵泡刺激素、黄体生成素、孕激素升高(P<0.05);试验组1和试验组2比较,差异无统计学意义(P>0.05)。与对照组相比,试验组1和试验组2性功能6个维度评分及总分均降低(P<0.05);与试验组1比较,试验组2性功能6个维度评分及总分均降低(P<0.05)。Logistic回归分析显示,年龄、绝经、体质指数(BMI)、糖化血红蛋白(HbA1c)、25羟维生素D为2型糖尿病伴FSD的危险因素。结论2型糖尿病患者FSD发病率明显高于非糖尿病患者,年龄、绝经、BMI、HbA1c、25羟维生素D是其主要危险因素。Objective To investigate the features of female sexual dysfunction(FSD)in type 2 diabetic patients(T2DM)and to analyze its risk factors.Methods From September 2022 to December 2023,252 female inpatients and outpatients with type 2 diabetes in the Endocrinology Department of our hospital were selected.According to FSFI indexes in the sexual function questionnaire,252 female T2DM patients were divided into experimental group 1(simple diabetes group)with 120 cases,and experimental group 2(diabetes+FSD)with 132 cases and 138 healthy women as the control group.The risk factors for FSD were analyzed using logistic regression analysis.Results The incidence of FSD in type 2 diabetes mellitus was 52.4%(132/252),which was higher than that in the control group[25.4%(35/138)].Compared with the control group,E2 in experimental group 1 and experimental group 2 decreased,and FSH,LH,and P increased(P<0.05).Comparing the same factors in experimental group 1 and experimental group 2(P>0.05).Compared with the control group,ratings on six dimensions of sexual function and overall rating for experimental group 1 and experimental group 2 decreased(P<0.05).Compared with experimental group 1,ratings on six dimensions of sexual function and overall rating decreased(P<0.05)in experimental group 2,logistic regression analysis showed that age,menopause,BMI,HbA1c,and 25-hydroxyvitamin D were risk factors for type 2 diabetes with FSD.Conclusion The prevalence of FSD in patients with type 2 diabetes is significantly higher than that in patients without diabetes,and age,menopause,BMI,HbA1c,and 25-hydroxyvitamin D are the main risk factors.

关 键 词：糖尿病 2型 性功能障碍 生理性 危险因素 

分 类 号：R587.1[医药卫生—内分泌] R711.77[医药卫生—内科学]