774例不同年龄段川崎病患儿的临床特征  

Clinical characteristics of 774 children with Kawasaki disease at different ages

作　　者：卢丹 王美芬[2] 郭皓[1] LU Dan;WANG Meifen;GUO Hao(Department of Cardiology,First Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650032,China;Department of Infection I,Kunming Children s Hospital,Kunming Yunnan 650228,China)

机构地区：[1]昆明医科大学第一附属医院心脏内科,云南昆明650032 [2]昆明市儿童医院感染一科,云南昆明650228

出　　处：《云南医药》2024年第5期17-20,共4页Medicine and Pharmacy of Yunnan

摘　　要：目的探讨不同年龄段KD患儿的发病情况及临床特征。方法回顾性分析2014年1月-2021年10月住院的774例KD患儿的临床资料,分析不同年龄组KD患儿的临床特征和并发症。结果各年龄组KD患儿均有发热,<1岁组卡疤红斑、腹泻、咳嗽、无菌性脑膜炎、肺炎发生率最高;1~3岁组皮疹发生率最高;低钾血症在3~6岁组发生率最高;>9岁组淋巴结肿大、结膜充血、口唇黏膜改变、头痛、低蛋白血症、低钙血症发生率最高。774例KD患儿按1岁分层后,提示<1岁的KD患儿CAD的发生率明显高于≥1岁的患儿,差异有统计学意义(P<0.05)。结论1岁以内及9岁以上KD患儿的典型临床表现更多,更易出现并发症;1岁以内是KD发生CAL的危险因素。Objective To explore the incidence and clinical features of children with Kawasaki disease(KD)at different ages.Methods We retrospectively analyzed the clinical data of 774 children with KD hospitalized from January 2014 to October 2021,and analyzed the clinical characteristics and complications of children with KD in different age groups.Results 1.All KD children in all age groups had fever,the highest incidence of cicatricial erythema,diarrhea,cough,aseptic meningitis and pneumonia was found in children under one year old group.The highest incidence of rash was found in the 1-3 years old group.Hypokalemia had the high within est incidence in the 3 to 6 years old group.Highest incidence of lymph node swelling,conjunctival congestion,mucosal changes of lips and mouth,headache,hypoproteinemia,hypocalcemia was found in elder than 9 years group.2.The 774 children with KD stratified according to one year old suggested that the incidence of CAD in children with KD<1 year of age was significantly higher than in that≥1 year of age,and the difference was statistically significant(P<0.005).Conclusions Children with KD under 1 year of age and elder than 9 years old have more typical clinical manifestations and are more likely to have complications.The risk factor for CAL in KD is within one year of age.

关 键 词：年龄 川崎病 临床表现 冠状动脉扩张 

分 类 号：R725.4[医药卫生—儿科]