毛细血管渗漏指数联合PLT等对肾综合征出血热AKI的预测价值  

Prediction value of capillary leakage index combined with PLT for acute kidney injury by renal syndrome hemorrhagic fever

作　　者：陈桂玉 何正宏 周骏 王之道 邓海燕 段迎梅 CHEN Guiyu;HE Zhenghong;ZHOU Jun;WANG Zhidao;DENG Haiyan;DUAN Yingmei(Department of Nephrology,Chuxiong Prefectural People s Hospital,Chuxiong Yunnan 675000,China)

机构地区：[1]楚雄州人民医院肾脏内科,云南楚雄675000

出　　处：《云南医药》2024年第5期34-38,共5页Medicine and Pharmacy of Yunnan

摘　　要：目的探讨毛细血管渗漏指数联合PLT等对肾综合征出血热所致AKI的预测价值。方法收集2020年10月-2024年5月收住楚雄州人民医院、确诊肾综合征出血热的患者112例,分为合并AKI组(71例)和非AKI组(41例)。采用多因素Logistic回归分析患者发生AKI的危险因素。采用受试者工作特征曲线评估毛细血管渗漏指数联合PLT对肾综合征出血热患者发生AKI的预测效能。结果WBC、NE、LYM、MO、PLT、PLR、ALB、CLI与肾综合征出血热患者的AKI发生率显著性相关差异有统计学意义(P<0.05);ROC曲线下面积最大为PLT联合CLI联合WBC联合PLR(0.759),多项指标联合预测肾综合征出血热患者发生AKI的特异性和敏感性优于单一指标。结论CLI联合PLT等指标预测肾综合征出血热患者发生AKI的效能高、简便、易重复,有重要临床价值。Objective This study aimed to explore the predictive value of capillary leakage index combined with platelet count(PLT)and others for acute kidney injury(AKI)caused by hemorrhagic fever with renal syndrome.Methods A total of 112 patients diagnosed with hemorrhagic fever with renal syndrome admitted to Chuxiong People's Hospital from October 2020 to May 2024 were collected and divided into AKI group(71 cases)and non-AKI group(41 cases).Multivariate logistic regression analysis was used to analyze the risk factors of AKI occurrence in patients.The efficacy of capillary leakage index combined with PLT in predicting AKI in patients with hemorrhagic fever with renal syndrome was evaluated by subject working characteristic curve.Results WBC,NE,LYM,MO,PLT,PLR,ALB and CLI were significantly correlated with AKI incidence in patients with hemorrhagic fever with renal syndrome(P均≤0.05).The maximum area under ROC curve was PLT combined with CLI,combined with WBC and combined with PLR(0.759).The specificity and sensitivity of multiple indexes in predicting AKI in patients with hemorrhagic fever with renal syndrome were better than that of a single index.Conclusions CLI combined with PLT is effective,simple and repeatable in predicting AKI in patients with hemorrhagic fever with renal syndrome,and has important clinical value.

关 键 词：毛细血管渗漏指数 血小板计数 肾综合征出血热 急性肾损伤 预测效能 

分 类 号：R512.8[医药卫生—内科学]