The Association Between Preserved Ratio Impaired Spirometry and Mortality –– 10 CKB Study Areas, China, 2004–2022  

作　　者：Yalei Ke Xinyi Zhang Dianjianyi Sun Pei Pei Huaidong Du Yiping Chen Ling Yang Xiaoming Yang Kang Wang Junshi Chen Zhengming Chen Jun Lv Liming Li Canqing Yu 

机构地区：[1]Department of Epidemiology and Biostatistics,School of Public Health,Peking University Health Science Center,Beijing,China [2]Peking University Center for Public Health and Epidemic Preparedness&Response,Beijing,China [3]Key Laboratory of Epidemiology of Major Diseases(Peking University),Ministry of Education,Beijing,China [4]Clinical Trial Service Unit&Epidemiological Studies Unit(CTSU),Nuffield Department of Population Health,University of Oxford,Oxford,UK [5]Shibei Center for Disease Control and Prevention,Qingdao City,Shandong Province,China [6]China National Center for Food Safety Risk Assessment,Beijing,China [7]State Key Laboratory of Vascular Homeostasis and Remodeling,Peking University,Beijing,China.

出　　处：《China CDC weekly》2024年第43期1120-1125,I0003,共7页中国疾病预防控制中心周报（英文）

基　　金：supported by the National Natural Science Foundation of China(82388102,82192900,82192901,82192904);The CKB baseline survey and the first re-survey were supported by a grant from the Kadoorie Charitable Foundation in Hong Kong;The long-term follow-up is supported by grants from the UK Wellcome Trust(212946/Z/18/Z,202922/Z/16/Z,104085/Z/14/Z,088158/Z/09/Z);grants(2016YFC0900500)from the National Key R&D Program of China,National Natural Science Foundation of China(81390540,91846303,81941018);Chinese Ministry of Science and Technology(2011BAI09B01)。

摘　　要：What is already known about this topic?China has the world’s most significant public health and economic burden of chronic respiratory disease.However,the association between preserved ratio impaired spirometry(PRISm)and mortality risk is unknown.What is added by this report?The PRISm group exhibited a 37%higher risk of allcause mortality than the normal group,and the risks of death from cardiovascular diseases,neoplasms,respiratory diseases,and infectious and parasitic diseases were also increased in PRISm.Moreover,the presence of respiratory symptoms or disease was associated with an increased risk of mortality in PRISm.What are the implications for public health practice?It is imperative to enhance public awareness of PRISm and to implement measures to facilitate the regression of PRISm toward normal lung function.

关 键 词：function IMPAIRED NEOPLASMS 

分 类 号：R563[医药卫生—呼吸系统]